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2xzd

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==Caspase-3 in Complex with an Inhibitory DARPin-3.4==
==Caspase-3 in Complex with an Inhibitory DARPin-3.4==
<StructureSection load='2xzd' size='340' side='right' caption='[[2xzd]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
<StructureSection load='2xzd' size='340' side='right' caption='[[2xzd]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2xzd]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XZD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2XZD FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2xzd]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human] and [http://en.wikipedia.org/wiki/Synthetic_construct_sequences Synthetic construct sequences]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XZD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2XZD FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=MRD:(4R)-2-METHYLPENTANE-2,4-DIOL'>MRD</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=MRD:(4R)-2-METHYLPENTANE-2,4-DIOL'>MRD</scene></td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene></td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1rhk|1rhk]], [[1rhq|1rhq]], [[2dko|2dko]], [[2xyp|2xyp]], [[2cjy|2cjy]], [[2j31|2j31]], [[2xyh|2xyh]], [[2cjx|2cjx]], [[1re1|1re1]], [[2xyg|2xyg]], [[2c1e|2c1e]], [[2cno|2cno]], [[1gfw|1gfw]], [[1qx3|1qx3]], [[1rhm|1rhm]], [[1nme|1nme]], [[2j33|2j33]], [[1rhr|1rhr]], [[1nms|1nms]], [[1nmq|1nmq]], [[1rhj|1rhj]], [[2cnn|2cnn]], [[2c2k|2c2k]], [[2cnl|2cnl]], [[2c2m|2c2m]], [[1cp3|1cp3]], [[2cnk|2cnk]], [[2j30|2j30]], [[1pau|1pau]], [[2cdr|2cdr]], [[2j32|2j32]], [[1i3o|1i3o]], [[1rhu|1rhu]], [[2c2o|2c2o]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1rhk|1rhk]], [[1rhq|1rhq]], [[2dko|2dko]], [[2xyp|2xyp]], [[2cjy|2cjy]], [[2j31|2j31]], [[2xyh|2xyh]], [[2cjx|2cjx]], [[1re1|1re1]], [[2xyg|2xyg]], [[2c1e|2c1e]], [[2cno|2cno]], [[1gfw|1gfw]], [[1qx3|1qx3]], [[1rhm|1rhm]], [[1nme|1nme]], [[2j33|2j33]], [[1rhr|1rhr]], [[1nms|1nms]], [[1nmq|1nmq]], [[1rhj|1rhj]], [[2cnn|2cnn]], [[2c2k|2c2k]], [[2cnl|2cnl]], [[2c2m|2c2m]], [[1cp3|1cp3]], [[2cnk|2cnk]], [[2j30|2j30]], [[1pau|1pau]], [[2cdr|2cdr]], [[2j32|2j32]], [[1i3o|1i3o]], [[1rhu|1rhu]], [[2c2o|2c2o]]</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Caspase-3 Caspase-3], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.22.56 3.4.22.56] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Caspase-3 Caspase-3], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.22.56 3.4.22.56] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2xzd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xzd OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2xzd RCSB], [http://www.ebi.ac.uk/pdbsum/2xzd PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2xzd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xzd OCA], [http://pdbe.org/2xzd PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2xzd RCSB], [http://www.ebi.ac.uk/pdbsum/2xzd PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2xzd ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 2xzd" style="background-color:#fffaf0;"></div>
==See Also==
==See Also==
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</StructureSection>
</StructureSection>
[[Category: Caspase-3]]
[[Category: Caspase-3]]
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[[Category: Homo sapiens]]
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[[Category: Human]]
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[[Category: Synthetic construct]]
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[[Category: Synthetic construct sequences]]
[[Category: Barandun, J]]
[[Category: Barandun, J]]
[[Category: Grutter, M G]]
[[Category: Grutter, M G]]

Revision as of 15:25, 4 August 2016

Caspase-3 in Complex with an Inhibitory DARPin-3.4

2xzd, resolution 2.10Å

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