3uo9
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| + | |||
==Crystal Structure of Human GAC in Complex with Glutamate and BPTES== | ==Crystal Structure of Human GAC in Complex with Glutamate and BPTES== | ||
<StructureSection load='3uo9' size='340' side='right' caption='[[3uo9]], [[Resolution|resolution]] 2.30Å' scene=''> | <StructureSection load='3uo9' size='340' side='right' caption='[[3uo9]], [[Resolution|resolution]] 2.30Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3uo9]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[3uo9]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UO9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3UO9 FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=04A:N,N-[SULFANEDIYLBIS(ETHANE-2,1-DIYL-1,3,4-THIADIAZOLE-5,2-DIYL)]BIS(2-PHENYLACETAMIDE)'>04A</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=04A:N,N-[SULFANEDIYLBIS(ETHANE-2,1-DIYL-1,3,4-THIADIAZOLE-5,2-DIYL)]BIS(2-PHENYLACETAMIDE)'>04A</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3unw|3unw]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3unw|3unw]]</td></tr> | ||
| - | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">GLS, GLS1, KIAA0838 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">GLS, GLS1, KIAA0838 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> |
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glutaminase Glutaminase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.2 3.5.1.2] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glutaminase Glutaminase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.2 3.5.1.2] </span></td></tr> | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3uo9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3uo9 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3uo9 RCSB], [http://www.ebi.ac.uk/pdbsum/3uo9 PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3uo9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3uo9 OCA], [http://pdbe.org/3uo9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3uo9 RCSB], [http://www.ebi.ac.uk/pdbsum/3uo9 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3uo9 ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| Line 19: | Line 20: | ||
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
| + | <div class="pdbe-citations 3uo9" style="background-color:#fffaf0;"></div> | ||
==See Also== | ==See Also== | ||
| Line 27: | Line 29: | ||
</StructureSection> | </StructureSection> | ||
[[Category: Glutaminase]] | [[Category: Glutaminase]] | ||
| - | [[Category: | + | [[Category: Human]] |
[[Category: Cheng, F]] | [[Category: Cheng, F]] | ||
[[Category: DeLaBarre, B]] | [[Category: DeLaBarre, B]] | ||
Revision as of 17:23, 4 August 2016
Crystal Structure of Human GAC in Complex with Glutamate and BPTES
| |||||||||||
Categories: Glutaminase | Human | Cheng, F | DeLaBarre, B | Gao, Y | Gross, S | Hurov, J B | Jha, A | Jiang, F | Song, J J | Wei, W | Hydrolase-hydrolase inhibitor complex
