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3p05

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==X-ray structure of pentameric HIV-1 CA==
==X-ray structure of pentameric HIV-1 CA==
<StructureSection load='3p05' size='340' side='right' caption='[[3p05]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
<StructureSection load='3p05' size='340' side='right' caption='[[3p05]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3p05]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3P05 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3P05 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3p05]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/9hiv1 9hiv1]. The July 2013 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''HIV Capsid'' by David Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2013_7 10.2210/rcsb_pdb/mom_2013_7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3P05 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3P05 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3h47|3h47]], [[3h4e|3h4e]], [[3gv2|3gv2]], [[2dik|2dik]], [[3p0a|3p0a]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3h47|3h47]], [[3h4e|3h4e]], [[3gv2|3gv2]], [[2dik|2dik]], [[3p0a|3p0a]]</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CA, gag ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11676 Human immunodeficiency virus 1])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CA, gag ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11676 9HIV1])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3p05 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3p05 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3p05 RCSB], [http://www.ebi.ac.uk/pdbsum/3p05 PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3p05 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3p05 OCA], [http://pdbe.org/3p05 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3p05 RCSB], [http://www.ebi.ac.uk/pdbsum/3p05 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3p05 ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/Q72497_9HIV1 Q72497_9HIV1]] Capsid protein p24 forms the conical core of the virus that encapsulates the genomic RNA-nucleocapsid complex (By similarity). Nucleocapsid protein p7 encapsulates and protects viral dimeric unspliced (genomic) RNA. Binds these RNAs through its zinc fingers (By similarity).[SAAS:SAAS012344_004_011858]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 3p05" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human immunodeficiency virus 1]]
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[[Category: HIV Capsid]]
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[[Category: RCSB PDB Molecule of the Month]]
[[Category: Pornillos, O]]
[[Category: Pornillos, O]]
[[Category: Capsid protein]]
[[Category: Capsid protein]]
[[Category: Viral protein]]
[[Category: Viral protein]]

Revision as of 18:31, 4 August 2016

X-ray structure of pentameric HIV-1 CA

3p05, resolution 2.50Å

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