3mha

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==Crystal structure of LprG from Mycobacterium tuberculosis bound to PIM==
==Crystal structure of LprG from Mycobacterium tuberculosis bound to PIM==
<StructureSection load='3mha' size='340' side='right' caption='[[3mha]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
<StructureSection load='3mha' size='340' side='right' caption='[[3mha]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3mha]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MHA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3MHA FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3mha]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Myctu Myctu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MHA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3MHA FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=Z69:(1S,2R,3R,4S,5R,6S)-2-(ALPHA-L-ALLOPYRANOSYLOXY)-3,4,5-TRIHYDROXY-6-({6-O-[(1R)-1-HYDROXYHEXADECYL]-BETA-L-GULOPYRANOSYL}OXY)CYCLOHEXYL+(2R)-2-{[(1S)-1-HYDROXYHEXADECYL]OXY}-3-{[(1S,10S)-1-HYDROXY-10-METHYLOCTADECYL]OXY}PROPYL+HYDROGEN+(R)-PHOSPHATE'>Z69</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=Z69:(1S,2R,3R,4S,5R,6S)-2-(ALPHA-L-ALLOPYRANOSYLOXY)-3,4,5-TRIHYDROXY-6-({6-O-[(1R)-1-HYDROXYHEXADECYL]-BETA-L-GULOPYRANOSYL}OXY)CYCLOHEXYL+(2R)-2-{[(1S)-1-HYDROXYHEXADECYL]OXY}-3-{[(1S,10S)-1-HYDROXY-10-METHYLOCTADECYL]OXY}PROPYL+HYDROGEN+(R)-PHOSPHATE'>Z69</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3mh8|3mh8]], [[3mh9|3mh9]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3mh8|3mh8]], [[3mh9|3mh9]]</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">lpp-27, lprG, MT1455, MTCY21B4.28c, Rv1411c ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1773 Mycobacterium tuberculosis])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">lpp-27, lprG, MT1455, MTCY21B4.28c, Rv1411c ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83332 MYCTU])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3mha FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3mha OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3mha RCSB], [http://www.ebi.ac.uk/pdbsum/3mha PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3mha FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3mha OCA], [http://pdbe.org/3mha PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3mha RCSB], [http://www.ebi.ac.uk/pdbsum/3mha PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3mha ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3mha ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 3mha" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Mycobacterium tuberculosis]]
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[[Category: Myctu]]
[[Category: Sacchettini, J C]]
[[Category: Sacchettini, J C]]
[[Category: Structural genomic]]
[[Category: Structural genomic]]

Revision as of 18:44, 4 August 2016

Crystal structure of LprG from Mycobacterium tuberculosis bound to PIM

3mha, resolution 1.85Å

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