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4afe

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==Nek2 bound to hybrid compound 21==
==Nek2 bound to hybrid compound 21==
<StructureSection load='4afe' size='340' side='right' caption='[[4afe]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
<StructureSection load='4afe' size='340' side='right' caption='[[4afe]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4afe]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AFE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4AFE FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4afe]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AFE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4AFE FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GGY:4-(2-AMINO-5-{4-[(DIMETHYLAMINO)METHYL]THIOPHEN-2-YL}PYRIDIN-3-YL)-2-{[(1R,2Z)-4,4,4-TRIFLUORO-1-METHYLBUT-2-EN-1-YL]OXY}BENZAMIDE'>GGY</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GGY:4-(2-AMINO-5-{4-[(DIMETHYLAMINO)METHYL]THIOPHEN-2-YL}PYRIDIN-3-YL)-2-{[(1R,2Z)-4,4,4-TRIFLUORO-1-METHYLBUT-2-EN-1-YL]OXY}BENZAMIDE'>GGY</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2xkc|2xkc]], [[2w5b|2w5b]], [[2xnp|2xnp]], [[2wqo|2wqo]], [[4a4x|4a4x]], [[2jav|2jav]], [[2xke|2xke]], [[2xkd|2xkd]], [[2xk7|2xk7]], [[2w5h|2w5h]], [[2xkf|2xkf]], [[2xk8|2xk8]], [[2xno|2xno]], [[2xk6|2xk6]], [[2xnn|2xnn]], [[2xk4|2xk4]], [[2xk3|2xk3]], [[2xnm|2xnm]], [[2w5a|2w5a]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2xkc|2xkc]], [[2w5b|2w5b]], [[2xnp|2xnp]], [[2wqo|2wqo]], [[4a4x|4a4x]], [[2jav|2jav]], [[2xke|2xke]], [[2xkd|2xkd]], [[2xk7|2xk7]], [[2w5h|2w5h]], [[2xkf|2xkf]], [[2xk8|2xk8]], [[2xno|2xno]], [[2xk6|2xk6]], [[2xnn|2xnn]], [[2xk4|2xk4]], [[2xk3|2xk3]], [[2xnm|2xnm]], [[2w5a|2w5a]]</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4afe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4afe OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4afe RCSB], [http://www.ebi.ac.uk/pdbsum/4afe PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4afe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4afe OCA], [http://pdbe.org/4afe PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4afe RCSB], [http://www.ebi.ac.uk/pdbsum/4afe PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4afe ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 4afe" style="background-color:#fffaf0;"></div>
==See Also==
==See Also==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Human]]
[[Category: Non-specific serine/threonine protein kinase]]
[[Category: Non-specific serine/threonine protein kinase]]
[[Category: Bayliss, R]]
[[Category: Bayliss, R]]

Revision as of 18:58, 4 August 2016

Nek2 bound to hybrid compound 21

4afe, resolution 2.60Å

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