4mgg
From Proteopedia
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==Crystal structure of an enolase (mandelate racemase subgroup) from labrenzia aggregata iam 12614 (target nysgrc-012903) with bound mg, space group p212121== | ==Crystal structure of an enolase (mandelate racemase subgroup) from labrenzia aggregata iam 12614 (target nysgrc-012903) with bound mg, space group p212121== | ||
<StructureSection load='4mgg' size='340' side='right' caption='[[4mgg]], [[Resolution|resolution]] 2.20Å' scene=''> | <StructureSection load='4mgg' size='340' side='right' caption='[[4mgg]], [[Resolution|resolution]] 2.20Å' scene=''> | ||
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene></td></tr> | ||
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">SIAM614_28497 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=384765 Labrenzia aggregata IAM 12614])</td></tr> | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">SIAM614_28497 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=384765 Labrenzia aggregata IAM 12614])</td></tr> | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4mgg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mgg OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4mgg RCSB], [http://www.ebi.ac.uk/pdbsum/4mgg PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4mgg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mgg OCA], [http://pdbe.org/4mgg PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4mgg RCSB], [http://www.ebi.ac.uk/pdbsum/4mgg PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4mgg ProSAT]</span></td></tr> |
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/C3HPD_LABAI C3HPD_LABAI]] Catalyzes the dehydration of cis-3-hydroxy-L-proline (c3LHyp) to Delta(1)-pyrroline-2-carboxylate (Pyr2C). Is likely involved in a degradation pathway that converts c3LHyp to L-proline, which allows L.aggregata to grow on c3LHyp as a sole carbon source. Also catalyzes the epimerization of c3LHyp to trans-3-hydroxy-D-proline (t3DHyp), a competing reaction occurring from the same enolate anion intermediate. L-proline, t3LHyp, t4LHyp, c4DHyp and their methylated derivatives are not substrates.<ref>PMID:25608448</ref> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
Revision as of 22:42, 4 August 2016
Crystal structure of an enolase (mandelate racemase subgroup) from labrenzia aggregata iam 12614 (target nysgrc-012903) with bound mg, space group p212121
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