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4a9u
From Proteopedia
(Difference between revisions)
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==CRYSTAL STRUCTURE OF HUMAN CHK2 IN COMPLEX WITH BENZIMIDAZOLE CARBOXAMIDE INHIBITOR== | ==CRYSTAL STRUCTURE OF HUMAN CHK2 IN COMPLEX WITH BENZIMIDAZOLE CARBOXAMIDE INHIBITOR== | ||
<StructureSection load='4a9u' size='340' side='right' caption='[[4a9u]], [[Resolution|resolution]] 2.48Å' scene=''> | <StructureSection load='4a9u' size='340' side='right' caption='[[4a9u]], [[Resolution|resolution]] 2.48Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4a9u]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[4a9u]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4A9U OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4A9U FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=A9U:2-{4-[(1-BENZYLPIPERIDIN-4-YL)METHOXY]PHENYL}-1H-BENZIMIDAZOLE-6-CARBOXAMIDE'>A9U</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=A9U:2-{4-[(1-BENZYLPIPERIDIN-4-YL)METHOXY]PHENYL}-1H-BENZIMIDAZOLE-6-CARBOXAMIDE'>A9U</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2wti|2wti]], [[2cn8|2cn8]], [[2ycf|2ycf]], [[2w0j|2w0j]], [[2yir|2yir]], [[2wtc|2wtc]], [[4a9r|4a9r]], [[2yit|2yit]], [[2ycr|2ycr]], [[2ycq|2ycq]], [[1gxc|1gxc]], [[2wtd|2wtd]], [[2xbj|2xbj]], [[2ycs|2ycs]], [[2wtj|2wtj]], [[2xk9|2xk9]], [[2xm9|2xm9]], [[2w7x|2w7x]], [[2cn5|2cn5]], [[2yiq|2yiq]], [[2xm8|2xm8]], [[4a9t|4a9t]], [[4a9s|4a9s]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2wti|2wti]], [[2cn8|2cn8]], [[2ycf|2ycf]], [[2w0j|2w0j]], [[2yir|2yir]], [[2wtc|2wtc]], [[4a9r|4a9r]], [[2yit|2yit]], [[2ycr|2ycr]], [[2ycq|2ycq]], [[1gxc|1gxc]], [[2wtd|2wtd]], [[2xbj|2xbj]], [[2ycs|2ycs]], [[2wtj|2wtj]], [[2xk9|2xk9]], [[2xm9|2xm9]], [[2w7x|2w7x]], [[2cn5|2cn5]], [[2yiq|2yiq]], [[2xm8|2xm8]], [[4a9t|4a9t]], [[4a9s|4a9s]]</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr> | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4a9u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4a9u OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4a9u RCSB], [http://www.ebi.ac.uk/pdbsum/4a9u PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4a9u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4a9u OCA], [http://pdbe.org/4a9u PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4a9u RCSB], [http://www.ebi.ac.uk/pdbsum/4a9u PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4a9u ProSAT]</span></td></tr> |
</table> | </table> | ||
== Disease == | == Disease == | ||
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
| + | <div class="pdbe-citations 4a9u" style="background-color:#fffaf0;"></div> | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Human]] |
[[Category: Non-specific serine/threonine protein kinase]] | [[Category: Non-specific serine/threonine protein kinase]] | ||
[[Category: Blagg, J]] | [[Category: Blagg, J]] | ||
Revision as of 23:26, 4 August 2016
CRYSTAL STRUCTURE OF HUMAN CHK2 IN COMPLEX WITH BENZIMIDAZOLE CARBOXAMIDE INHIBITOR
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