This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
2y2u
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| + | |||
==NONAGED FORM OF MOUSE ACETYLCHOLINESTERASE INHIBITED BY VX-UPDATE== | ==NONAGED FORM OF MOUSE ACETYLCHOLINESTERASE INHIBITED BY VX-UPDATE== | ||
<StructureSection load='2y2u' size='340' side='right' caption='[[2y2u]], [[Resolution|resolution]] 2.60Å' scene=''> | <StructureSection load='2y2u' size='340' side='right' caption='[[2y2u]], [[Resolution|resolution]] 2.60Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2y2u]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[2y2u]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2jgh 2jgh]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Y2U OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2Y2U FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=P33:3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL'>P33</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=P33:3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL'>P33</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr> | ||
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=SVX:O-[(R)-ETHOXY(METHYL)PHOSPHORYL]-L-SERINE'>SVX</scene></td></tr> | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=SVX:O-[(R)-ETHOXY(METHYL)PHOSPHORYL]-L-SERINE'>SVX</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2whq|2whq]], [[2jgh|2jgh]], [[1mah|1mah]], [[2ha6|2ha6]], [[1maa|1maa]], [[2jgg|2jgg]], [[2c0q|2c0q]], [[2jgl|2jgl]], [[2xug|2xug]], [[1q84|1q84]], [[2xud|2xud]], [[2jgm|2jgm]], [[2xuj|2xuj]], [[1q83|1q83]], [[2jge|2jge]], [[2wls|2wls]], [[2xup|2xup]], [[2xuk|2xuk]], [[2ha3|2ha3]], [[1c2b|1c2b]], [[2ha0|2ha0]], [[2xuf|2xuf]], [[2wu3|2wu3]], [[2jey|2jey]], [[2jgi|2jgi]], [[1n5r|1n5r]], [[2xuh|2xuh]], [[2jgj|2jgj]], [[1j06|1j06]], [[2jf0|2jf0]], [[2c0p|2c0p]], [[2xuo|2xuo]], [[2xui|2xui]], [[2whr|2whr]], [[2h9y|2h9y]], [[1n5m|1n5m]], [[2xuq|2xuq]], [[2ha2|2ha2]], [[2ha5|2ha5]], [[2whp|2whp]], [[4a23|4a23]], [[2jez|2jez]], [[2jgk|2jgk]], [[1ku6|1ku6]], [[2ha4|2ha4]], [[1j07|1j07]], [[2jgf|2jgf]], [[2ha7|2ha7]], [[2wu4|2wu4]], [[2y2v|2y2v]], [[4a16|4a16]], [[1c2o|1c2o]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2whq|2whq]], [[2jgh|2jgh]], [[1mah|1mah]], [[2ha6|2ha6]], [[1maa|1maa]], [[2jgg|2jgg]], [[2c0q|2c0q]], [[2jgl|2jgl]], [[2xug|2xug]], [[1q84|1q84]], [[2xud|2xud]], [[2jgm|2jgm]], [[2xuj|2xuj]], [[1q83|1q83]], [[2jge|2jge]], [[2wls|2wls]], [[2xup|2xup]], [[2xuk|2xuk]], [[2ha3|2ha3]], [[1c2b|1c2b]], [[2ha0|2ha0]], [[2xuf|2xuf]], [[2wu3|2wu3]], [[2jey|2jey]], [[2jgi|2jgi]], [[1n5r|1n5r]], [[2xuh|2xuh]], [[2jgj|2jgj]], [[1j06|1j06]], [[2jf0|2jf0]], [[2c0p|2c0p]], [[2xuo|2xuo]], [[2xui|2xui]], [[2whr|2whr]], [[2h9y|2h9y]], [[1n5m|1n5m]], [[2xuq|2xuq]], [[2ha2|2ha2]], [[2ha5|2ha5]], [[2whp|2whp]], [[4a23|4a23]], [[2jez|2jez]], [[2jgk|2jgk]], [[1ku6|1ku6]], [[2ha4|2ha4]], [[1j07|1j07]], [[2jgf|2jgf]], [[2ha7|2ha7]], [[2wu4|2wu4]], [[2y2v|2y2v]], [[4a16|4a16]], [[1c2o|1c2o]]</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Acetylcholinesterase Acetylcholinesterase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.7 3.1.1.7] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Acetylcholinesterase Acetylcholinesterase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.7 3.1.1.7] </span></td></tr> | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2y2u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2y2u OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2y2u RCSB], [http://www.ebi.ac.uk/pdbsum/2y2u PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2y2u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2y2u OCA], [http://pdbe.org/2y2u PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2y2u RCSB], [http://www.ebi.ac.uk/pdbsum/2y2u PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2y2u ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| Line 14: | Line 15: | ||
==See Also== | ==See Also== | ||
*[[Acetylcholinesterase|Acetylcholinesterase]] | *[[Acetylcholinesterase|Acetylcholinesterase]] | ||
| + | *[[3D structures of acetylcholinesterase|3D structures of acetylcholinesterase]] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Acetylcholinesterase]] | [[Category: Acetylcholinesterase]] | ||
| - | [[Category: | + | [[Category: Lk3 transgenic mice]] |
[[Category: Akfur, C]] | [[Category: Akfur, C]] | ||
[[Category: Artursson, E]] | [[Category: Artursson, E]] | ||
Revision as of 00:03, 5 August 2016
NONAGED FORM OF MOUSE ACETYLCHOLINESTERASE INHIBITED BY VX-UPDATE
| |||||||||||
