3pec
From Proteopedia
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==Siderocalin Recognitin of Carboxymycobactins: Interference by the immune system in intracellular iron acquisition by Mycobacteria tuberculosis== | ==Siderocalin Recognitin of Carboxymycobactins: Interference by the immune system in intracellular iron acquisition by Mycobacteria tuberculosis== | ||
<StructureSection load='3pec' size='340' side='right' caption='[[3pec]], [[Resolution|resolution]] 2.19Å' scene=''> | <StructureSection load='3pec' size='340' side='right' caption='[[3pec]], [[Resolution|resolution]] 2.19Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3pec]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[3pec]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PEC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3PEC FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZYG:9-{HYDROXY[(5S,6R)-6-HYDROXY-6-{[(1S)-3-{[(3S)-1-HYDROXY-2-OXOAZEPAN-3-YL]AMINO}-1-METHYL-3-OXOPROPYL]OXY}-5-({[(4S)-2-(2-HYDROXYPHENYL)-4,5-DIHYDRO-1,3-OXAZOL-4-YL]CARBONYL}AMINO)HEXYL]AMINO}-9-OXONONANOIC+ACID'>ZYG</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZYG:9-{HYDROXY[(5S,6R)-6-HYDROXY-6-{[(1S)-3-{[(3S)-1-HYDROXY-2-OXOAZEPAN-3-YL]AMINO}-1-METHYL-3-OXOPROPYL]OXY}-5-({[(4S)-2-(2-HYDROXYPHENYL)-4,5-DIHYDRO-1,3-OXAZOL-4-YL]CARBONYL}AMINO)HEXYL]AMINO}-9-OXONONANOIC+ACID'>ZYG</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1x89|1x89]], [[1x8u|1x8u]], [[3ped|3ped]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1x89|1x89]], [[1x8u|1x8u]], [[3ped|3ped]]</td></tr> | ||
| - | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">LCN2, HNL, NGAL ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">LCN2, HNL, NGAL ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3pec FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pec OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3pec RCSB], [http://www.ebi.ac.uk/pdbsum/3pec PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3pec FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pec OCA], [http://pdbe.org/3pec PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3pec RCSB], [http://www.ebi.ac.uk/pdbsum/3pec PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3pec ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Human]] |
[[Category: Clifton, M C]] | [[Category: Clifton, M C]] | ||
[[Category: 8-stranded anti-parallel beta barrel]] | [[Category: 8-stranded anti-parallel beta barrel]] | ||
Revision as of 01:36, 5 August 2016
Siderocalin Recognitin of Carboxymycobactins: Interference by the immune system in intracellular iron acquisition by Mycobacteria tuberculosis
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