1lpi
From Proteopedia
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|PDB= 1lpi |SIZE=350|CAPTION= <scene name='initialview01'>1lpi</scene>, resolution 2.00Å | |PDB= 1lpi |SIZE=350|CAPTION= <scene name='initialview01'>1lpi</scene>, resolution 2.00Å | ||
|SITE= <scene name='pdbsite=PON:Binding+Site+Of+A+Na+Cation+Stabilized+By+Pi-Cation+Inte+...'>PON</scene> | |SITE= <scene name='pdbsite=PON:Binding+Site+Of+A+Na+Cation+Stabilized+By+Pi-Cation+Inte+...'>PON</scene> | ||
| - | |LIGAND= <scene name='pdbligand=NA:SODIUM ION'>NA</scene> | + | |LIGAND= <scene name='pdbligand=NA:SODIUM+ION'>NA</scene> |
| - | |ACTIVITY= [http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] | + | |ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span> |
|GENE= | |GENE= | ||
| + | |DOMAIN= | ||
| + | |RELATEDENTRY= | ||
| + | |RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1lpi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1lpi OCA], [http://www.ebi.ac.uk/pdbsum/1lpi PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1lpi RCSB]</span> | ||
}} | }} | ||
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[[Category: Single protein]] | [[Category: Single protein]] | ||
[[Category: Wouters, J.]] | [[Category: Wouters, J.]] | ||
| - | [[Category: NA]] | ||
[[Category: glycosidase]] | [[Category: glycosidase]] | ||
[[Category: hydrolase]] | [[Category: hydrolase]] | ||
[[Category: o-glycosyl]] | [[Category: o-glycosyl]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 22:05:43 2008'' |
Revision as of 19:05, 30 March 2008
| |||||||
| , resolution 2.00Å | |||||||
|---|---|---|---|---|---|---|---|
| Sites: | |||||||
| Ligands: | |||||||
| Activity: | Lysozyme, with EC number 3.2.1.17 | ||||||
| Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
HEW LYSOZYME: TRP...NA CATION-PI INTERACTION
Overview
Experimental evidence of a cation-pi interaction between a sodium cation (Na+) and the indole ring of residue Trp123 in a structure (2.0 A) of hen egg-white lysozyme is presented. The geometry of the metal ion-pi interaction observed in the protein structure (distance between the aromatic plane and the cation approximately 4 A) is consistent with geometries observed among small molecules crystal structures and quantum chemistry ab initio calculations. The present crystal structure of lysozyme provides unique structural information about the geometry of binding of cations to pi systems in proteins. It shows that the metal ion-pi interaction within proteins is not significantly different from similar bindings found in small molecules and that it can be modeled by theoretical methods.
About this Structure
1LPI is a Single protein structure of sequence from Gallus gallus. Full crystallographic information is available from OCA.
Reference
Cation-pi (Na+-Trp) interactions in the crystal structure of tetragonal lysozyme., Wouters J, Protein Sci. 1998 Nov;7(11):2472-5. PMID:9828016
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