This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
3r2b
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| + | |||
==MK2 kinase bound to Compound 5b== | ==MK2 kinase bound to Compound 5b== | ||
<StructureSection load='3r2b' size='340' side='right' caption='[[3r2b]], [[Resolution|resolution]] 2.90Å' scene=''> | <StructureSection load='3r2b' size='340' side='right' caption='[[3r2b]], [[Resolution|resolution]] 2.90Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3r2b]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[3r2b]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3R2B OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3R2B FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=05B:2-[2-(1,3-BENZODIOXOL-5-YL)PYRIMIDIN-4-YL]-5,6-DIHYDROSPIRO[PIPERIDINE-4,7-PYRROLO[3,2-C]PYRIDIN]-4(1H)-ONE'>05B</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=05B:2-[2-(1,3-BENZODIOXOL-5-YL)PYRIMIDIN-4-YL]-5,6-DIHYDROSPIRO[PIPERIDINE-4,7-PYRROLO[3,2-C]PYRIDIN]-4(1H)-ONE'>05B</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3r1n|3r1n]], [[3r2y|3r2y]], [[3r30|3r30]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3r1n|3r1n]], [[3r2y|3r2y]], [[3r30|3r30]]</td></tr> | ||
| - | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MAPKAPK2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MAPKAPK2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> |
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr> | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3r2b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3r2b OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3r2b RCSB], [http://www.ebi.ac.uk/pdbsum/3r2b PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3r2b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3r2b OCA], [http://pdbe.org/3r2b PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3r2b RCSB], [http://www.ebi.ac.uk/pdbsum/3r2b PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3r2b ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| Line 19: | Line 20: | ||
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
| + | <div class="pdbe-citations 3r2b" style="background-color:#fffaf0;"></div> | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Human]] |
[[Category: Non-specific serine/threonine protein kinase]] | [[Category: Non-specific serine/threonine protein kinase]] | ||
[[Category: Oubrie, A]] | [[Category: Oubrie, A]] | ||
Revision as of 03:25, 5 August 2016
MK2 kinase bound to Compound 5b
| |||||||||||
