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3k7v
From Proteopedia
(Difference between revisions)
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==Protein phosphatase 2A core complex bound to dinophysistoxin-1== | ==Protein phosphatase 2A core complex bound to dinophysistoxin-1== | ||
<StructureSection load='3k7v' size='340' side='right' caption='[[3k7v]], [[Resolution|resolution]] 2.85Å' scene=''> | <StructureSection load='3k7v' size='340' side='right' caption='[[3k7v]], [[Resolution|resolution]] 2.85Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3k7v]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[3k7v]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3K7V OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3K7V FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=XT1:(2R)-3-[(2S,5R,6R,8S)-8-{(1R,2E)-3-[(2R,4AR,5R,6S,8R,8AS)-6-{(1S,3S)-3-[(2S,3R,6R,11R)-3,11-DIMETHYL-1,7-DIOXASPIRO[5.5]UNDEC-2-YL]-1-HYDROXYBUTYL}-8-HYDROXY-7-METHYLIDENEOCTAHYDRO-3H,3H-SPIRO[FURAN-2,2-PYRANO[3,2-B]PYRAN]-5-YL]-1-METHYLPROP-2-EN-1-YL}-5-HYDROXY-10-METHYL-1,7-DIOXASPIRO[5.5]UNDEC-10-EN-2-YL]-2-HYDROXY-2-METHYLPROPANOIC+ACID'>XT1</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=XT1:(2R)-3-[(2S,5R,6R,8S)-8-{(1R,2E)-3-[(2R,4AR,5R,6S,8R,8AS)-6-{(1S,3S)-3-[(2S,3R,6R,11R)-3,11-DIMETHYL-1,7-DIOXASPIRO[5.5]UNDEC-2-YL]-1-HYDROXYBUTYL}-8-HYDROXY-7-METHYLIDENEOCTAHYDRO-3H,3H-SPIRO[FURAN-2,2-PYRANO[3,2-B]PYRAN]-5-YL]-1-METHYLPROP-2-EN-1-YL}-5-HYDROXY-10-METHYL-1,7-DIOXASPIRO[5.5]UNDEC-10-EN-2-YL]-2-HYDROXY-2-METHYLPROPANOIC+ACID'>XT1</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2ie4|2ie4]], [[3k7w|3k7w]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2ie4|2ie4]], [[3k7w|3k7w]]</td></tr> | ||
| - | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PPP2R1A ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PPP2R1A ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN]), PPP2CA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> |
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Phosphoprotein_phosphatase Phosphoprotein phosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.16 3.1.3.16] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Phosphoprotein_phosphatase Phosphoprotein phosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.16 3.1.3.16] </span></td></tr> | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3k7v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3k7v OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3k7v RCSB], [http://www.ebi.ac.uk/pdbsum/3k7v PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3k7v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3k7v OCA], [http://pdbe.org/3k7v PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3k7v RCSB], [http://www.ebi.ac.uk/pdbsum/3k7v PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3k7v ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
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<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
| - | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/ | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3k7v ConSurf]. |
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
| + | <div class="pdbe-citations 3k7v" style="background-color:#fffaf0;"></div> | ||
==See Also== | ==See Also== | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Human]] |
[[Category: Phosphoprotein phosphatase]] | [[Category: Phosphoprotein phosphatase]] | ||
[[Category: Huhn, J]] | [[Category: Huhn, J]] | ||
Revision as of 04:38, 5 August 2016
Protein phosphatase 2A core complex bound to dinophysistoxin-1
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Categories: Human | Phosphoprotein phosphatase | Huhn, J | Jeffrey, P D | Shi, Y | Centromere | Cytoskeleton | Heat repeat | Hydrolase | Iron | Ligand specificity | Manganese | Metal-binding | Methylation | Nucleus | Phosphatase | Phosphoprotein | Protein phosphatase | Protein-protein complex | Signaling protein | Signaling protein-hydrolase complex
