4mq4

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==Crystal Structure of hPNMT in Complex with bisubstrate inhibitor N-(3-((((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl)thio)propyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxamide==
==Crystal Structure of hPNMT in Complex with bisubstrate inhibitor N-(3-((((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl)thio)propyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxamide==
<StructureSection load='4mq4' size='340' side='right' caption='[[4mq4]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
<StructureSection load='4mq4' size='340' side='right' caption='[[4mq4]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1hnn|1hnn]], [[2g72|2g72]], [[4mik|4mik]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1hnn|1hnn]], [[2g72|2g72]], [[4mik|4mik]]</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Phenylethanolamine_N-methyltransferase Phenylethanolamine N-methyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.28 2.1.1.28] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Phenylethanolamine_N-methyltransferase Phenylethanolamine N-methyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.28 2.1.1.28] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4mq4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mq4 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4mq4 RCSB], [http://www.ebi.ac.uk/pdbsum/4mq4 PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4mq4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mq4 OCA], [http://pdbe.org/4mq4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4mq4 RCSB], [http://www.ebi.ac.uk/pdbsum/4mq4 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4mq4 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/PNMT_HUMAN PNMT_HUMAN]] Converts noradrenaline to adrenaline.
[[http://www.uniprot.org/uniprot/PNMT_HUMAN PNMT_HUMAN]] Converts noradrenaline to adrenaline.
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==See Also==
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*[[Phenylethanolamine N-methyltransferase|Phenylethanolamine N-methyltransferase]]
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__TOC__
</StructureSection>
</StructureSection>

Revision as of 05:41, 5 August 2016

Crystal Structure of hPNMT in Complex with bisubstrate inhibitor N-(3-((((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl)thio)propyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxamide

4mq4, resolution 2.20Å

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