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4alg
From Proteopedia
(Difference between revisions)
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==N-Terminal Bromodomain of Human BRD2 With IBET-151== | ==N-Terminal Bromodomain of Human BRD2 With IBET-151== | ||
<StructureSection load='4alg' size='340' side='right' caption='[[4alg]], [[Resolution|resolution]] 1.60Å' scene=''> | <StructureSection load='4alg' size='340' side='right' caption='[[4alg]], [[Resolution|resolution]] 1.60Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4alg]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[4alg]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ALG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ALG FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1GH:7-(3,5-DIMETHYL-1,2-OXAZOL-4-YL)-8-METHOXY-1-[(1R)-1-(PYRIDIN-2-YL)ETHYL]-1H,2H,3H-IMIDAZO[4,5-C]QUINOLIN-2-ONE'>1GH</scene>, <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1GH:7-(3,5-DIMETHYL-1,2-OXAZOL-4-YL)-8-METHOXY-1-[(1R)-1-(PYRIDIN-2-YL)ETHYL]-1H,2H,3H-IMIDAZO[4,5-C]QUINOLIN-2-ONE'>1GH</scene>, <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1x0j|1x0j]], [[2ydw|2ydw]], [[2yek|2yek]], [[4a9e|4a9e]], [[4a9f|4a9f]], [[4a9h|4a9h]], [[4a9i|4a9i]], [[4a9j|4a9j]], [[4a9m|4a9m]], [[4a9n|4a9n]], [[4a9o|4a9o]], [[4akn|4akn]], [[4alh|4alh]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1x0j|1x0j]], [[2ydw|2ydw]], [[2yek|2yek]], [[4a9e|4a9e]], [[4a9f|4a9f]], [[4a9h|4a9h]], [[4a9i|4a9i]], [[4a9j|4a9j]], [[4a9m|4a9m]], [[4a9n|4a9n]], [[4a9o|4a9o]], [[4akn|4akn]], [[4alh|4alh]]</td></tr> | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4alg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4alg OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4alg RCSB], [http://www.ebi.ac.uk/pdbsum/4alg PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4alg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4alg OCA], [http://pdbe.org/4alg PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4alg RCSB], [http://www.ebi.ac.uk/pdbsum/4alg PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4alg ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
| + | <div class="pdbe-citations 4alg" style="background-color:#fffaf0;"></div> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Bromodomain-containing protein|Bromodomain-containing protein]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Human]] |
[[Category: Bouillot, A]] | [[Category: Bouillot, A]] | ||
[[Category: Chung, C]] | [[Category: Chung, C]] | ||
Revision as of 06:00, 5 August 2016
N-Terminal Bromodomain of Human BRD2 With IBET-151
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Categories: Human | Bouillot, A | Chung, C | Donche, F | Lamotte, Y | Mirguet, O | Epigenetic reader | Histone | Inhibitor | Signaling protein
