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4bi2
From Proteopedia
(Difference between revisions)
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==Scaffold Focused Virtual Screening: Prospective Application to the Discovery of TTK Inhibitor== | ==Scaffold Focused Virtual Screening: Prospective Application to the Discovery of TTK Inhibitor== | ||
<StructureSection load='4bi2' size='340' side='right' caption='[[4bi2]], [[Resolution|resolution]] 3.11Å' scene=''> | <StructureSection load='4bi2' size='340' side='right' caption='[[4bi2]], [[Resolution|resolution]] 3.11Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4bi2]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[4bi2]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BI2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4BI2 FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=7PE:2-(2-(2-(2-(2-(2-ETHOXYETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHANOL'>7PE</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=ZO8:THIENO[2,3-C][2,7]NAPHTHYRIDINE'>ZO8</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=7PE:2-(2-(2-(2-(2-(2-ETHOXYETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHANOL'>7PE</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=ZO8:THIENO[2,3-C][2,7]NAPHTHYRIDINE'>ZO8</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4bhz|4bhz]], [[4bi0|4bi0]], [[4bi1|4bi1]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4bhz|4bhz]], [[4bi0|4bi0]], [[4bi1|4bi1]]</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Dual-specificity_kinase Dual-specificity kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.12.1 2.7.12.1] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Dual-specificity_kinase Dual-specificity kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.12.1 2.7.12.1] </span></td></tr> | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4bi2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bi2 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4bi2 RCSB], [http://www.ebi.ac.uk/pdbsum/4bi2 PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4bi2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bi2 OCA], [http://pdbe.org/4bi2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4bi2 RCSB], [http://www.ebi.ac.uk/pdbsum/4bi2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4bi2 ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
| + | <div class="pdbe-citations 4bi2" style="background-color:#fffaf0;"></div> | ||
==See Also== | ==See Also== | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Dual-specificity kinase]] | [[Category: Dual-specificity kinase]] | ||
| - | [[Category: | + | [[Category: Human]] |
[[Category: Blagg, J]] | [[Category: Blagg, J]] | ||
[[Category: Brown, N]] | [[Category: Brown, N]] | ||
Revision as of 06:41, 5 August 2016
Scaffold Focused Virtual Screening: Prospective Application to the Discovery of TTK Inhibitor
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