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4fcd
From Proteopedia
(Difference between revisions)
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==Potent and Selective Phosphodiesterase 10A Inhibitors== | ==Potent and Selective Phosphodiesterase 10A Inhibitors== | ||
<StructureSection load='4fcd' size='340' side='right' caption='[[4fcd]], [[Resolution|resolution]] 2.02Å' scene=''> | <StructureSection load='4fcd' size='340' side='right' caption='[[4fcd]], [[Resolution|resolution]] 2.02Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4fcd]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[4fcd]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FCD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4FCD FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=0T6:1-(2-CHLOROPHENYL)-6,8-DIMETHOXY-3-METHYLIMIDAZO[5,1-C][1,2,4]BENZOTRIAZINE'>0T6</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=0T6:1-(2-CHLOROPHENYL)-6,8-DIMETHOXY-3-METHYLIMIDAZO[5,1-C][1,2,4]BENZOTRIAZINE'>0T6</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4fcb|4fcb]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4fcb|4fcb]]</td></tr> | ||
| - | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PDE10A ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PDE10A ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4fcd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4fcd OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4fcd RCSB], [http://www.ebi.ac.uk/pdbsum/4fcd PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4fcd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4fcd OCA], [http://pdbe.org/4fcd PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4fcd RCSB], [http://www.ebi.ac.uk/pdbsum/4fcd PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4fcd ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
| + | <div class="pdbe-citations 4fcd" style="background-color:#fffaf0;"></div> | ||
==See Also== | ==See Also== | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Human]] |
[[Category: Parris, K D]] | [[Category: Parris, K D]] | ||
[[Category: Binding site]] | [[Category: Binding site]] | ||
[[Category: Cyclic amp]] | [[Category: Cyclic amp]] | ||
[[Category: Cyclic gmp]] | [[Category: Cyclic gmp]] | ||
| - | [[Category: Human]] | ||
[[Category: Hydrolase-hydrolase inhibitor complex]] | [[Category: Hydrolase-hydrolase inhibitor complex]] | ||
[[Category: Hydrolysis]] | [[Category: Hydrolysis]] | ||
Revision as of 06:49, 5 August 2016
Potent and Selective Phosphodiesterase 10A Inhibitors
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