3msv
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| + | |||
==The hypoxic regulator of sterol synthesis Nro1 is a nuclear import adaptor== | ==The hypoxic regulator of sterol synthesis Nro1 is a nuclear import adaptor== | ||
<StructureSection load='3msv' size='340' side='right' caption='[[3msv]], [[Resolution|resolution]] 2.18Å' scene=''> | <StructureSection load='3msv' size='340' side='right' caption='[[3msv]], [[Resolution|resolution]] 2.18Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3msv]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[3msv]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Cbs_356 Cbs 356]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MSV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3MSV FirstGlance]. <br> |
| - | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">SPCC4B3.07 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4896 | + | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">SPCC4B3.07 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4896 CBS 356])</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3msv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3msv OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3msv RCSB], [http://www.ebi.ac.uk/pdbsum/3msv PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3msv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3msv OCA], [http://pdbe.org/3msv PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3msv RCSB], [http://www.ebi.ac.uk/pdbsum/3msv PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3msv ProSAT]</span></td></tr> |
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/ETT1_SCHPO ETT1_SCHPO]] Required for correct translation termination (By similarity). Positive regulator of the stability of the N-terminal transcription factor domain (Sre1N) of sre1 which is released from the membrane and enters the nucleus to activate hypoxic gene expression. Acts also as a direct inhibitor of ofd1. Functions probably by inhibiting the ability of the ofd1 to accelerate Sre1N degradation in absence of oxygen.<ref>PMID:15116432</ref> <ref>PMID:19158663</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
| Line 14: | Line 17: | ||
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
| + | <div class="pdbe-citations 3msv" style="background-color:#fffaf0;"></div> | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Cbs 356]] |
[[Category: Amzel, L M]] | [[Category: Amzel, L M]] | ||
[[Category: Bianchet, M A]] | [[Category: Bianchet, M A]] | ||
Revision as of 07:41, 5 August 2016
The hypoxic regulator of sterol synthesis Nro1 is a nuclear import adaptor
| |||||||||||
