3q7j
From Proteopedia
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==Engineered Thermoplasma Acidophilum F3 factor mimics human aminopeptidase N (APN) as a target for anticancer drug development== | ==Engineered Thermoplasma Acidophilum F3 factor mimics human aminopeptidase N (APN) as a target for anticancer drug development== | ||
<StructureSection load='3q7j' size='340' side='right' caption='[[3q7j]], [[Resolution|resolution]] 2.91Å' scene=''> | <StructureSection load='3q7j' size='340' side='right' caption='[[3q7j]], [[Resolution|resolution]] 2.91Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3q7j]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[3q7j]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Theac Theac]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q7J OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3Q7J FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FBO:L-PHENYLALANYL-N6-[(BENZYLOXY)CARBONYL]-N1-HYDROXY-L-LYSINAMIDE'>FBO</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FBO:L-PHENYLALANYL-N6-[(BENZYLOXY)CARBONYL]-N1-HYDROXY-L-LYSINAMIDE'>FBO</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
| - | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">O93655, Ta0815, trf3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id= | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">O93655, Ta0815, trf3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=273075 THEAC])</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3q7j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3q7j OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3q7j RCSB], [http://www.ebi.ac.uk/pdbsum/3q7j PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3q7j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3q7j OCA], [http://pdbe.org/3q7j PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3q7j RCSB], [http://www.ebi.ac.uk/pdbsum/3q7j PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3q7j ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
| + | <div class="pdbe-citations 3q7j" style="background-color:#fffaf0;"></div> | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Theac]] |
[[Category: Feng, J]] | [[Category: Feng, J]] | ||
[[Category: Gu, L]] | [[Category: Gu, L]] | ||
Revision as of 08:25, 5 August 2016
Engineered Thermoplasma Acidophilum F3 factor mimics human aminopeptidase N (APN) as a target for anticancer drug development
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Categories: Theac | Feng, J | Gu, L | Su, J | Wang, Q | We, T | Xu, W | Zhang, C | Zhu, D | Aminopeptidase | Hydrolase-hydrolase inhibitor complex | Inhibitor binding | Inhibitor fbo | Trf3
