3tz4
From Proteopedia
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==Crystal structure of branched-chain alpha-ketoacid dehydrogenase kinase/S-alpha-chloroisocaproate complex with ADP== | ==Crystal structure of branched-chain alpha-ketoacid dehydrogenase kinase/S-alpha-chloroisocaproate complex with ADP== | ||
<StructureSection load='3tz4' size='340' side='right' caption='[[3tz4]], [[Resolution|resolution]] 2.25Å' scene=''> | <StructureSection load='3tz4' size='340' side='right' caption='[[3tz4]], [[Resolution|resolution]] 2.25Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3tz4]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[3tz4]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Buffalo_rat Buffalo rat]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TZ4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3TZ4 FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=03H:(2S)-2-CHLORO-4-METHYLPENTANOIC+ACID'>03H</scene>, <scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=03H:(2S)-2-CHLORO-4-METHYLPENTANOIC+ACID'>03H</scene>, <scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3tz0|3tz0]], [[3tz2|3tz2]], [[3tz5|3tz5]], [[4dzy|4dzy]], [[4h7q|4h7q]], [[4h81|4h81]], [[4h85|4h85]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3tz0|3tz0]], [[3tz2|3tz2]], [[3tz5|3tz5]], [[4dzy|4dzy]], [[4h7q|4h7q]], [[4h81|4h81]], [[4h85|4h85]]</td></tr> | ||
| - | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Bckdk ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10116 | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Bckdk ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10116 Buffalo rat])</td></tr> |
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/[3-methyl-2-oxobutanoate_dehydrogenase_(acetyl-transferring)]_kinase [3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring)] kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.4 2.7.11.4] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/[3-methyl-2-oxobutanoate_dehydrogenase_(acetyl-transferring)]_kinase [3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring)] kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.4 2.7.11.4] </span></td></tr> | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3tz4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tz4 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3tz4 RCSB], [http://www.ebi.ac.uk/pdbsum/3tz4 PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3tz4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tz4 OCA], [http://pdbe.org/3tz4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3tz4 RCSB], [http://www.ebi.ac.uk/pdbsum/3tz4 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3tz4 ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Buffalo rat]] |
[[Category: Chuang, D T]] | [[Category: Chuang, D T]] | ||
[[Category: Chuang, J L]] | [[Category: Chuang, J L]] | ||
Revision as of 10:01, 5 August 2016
Crystal structure of branched-chain alpha-ketoacid dehydrogenase kinase/S-alpha-chloroisocaproate complex with ADP
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Categories: Buffalo rat | Chuang, D T | Chuang, J L | Gui, W J | Li, J | Tso, S C | Wynn, R M | Allosteric kinase inhibitor | Bergerat nucleotide-binding fold | Branched-chain alpha-ketoacid | Branched-chain amino acid | Diabetes and obesity | Ghkl protein kinase | Maple syrup urine disease | Protein kinase | Transferase-transferase inhibitor complex
