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1mem

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|PDB= 1mem |SIZE=350|CAPTION= <scene name='initialview01'>1mem</scene>, resolution 1.8&Aring;
|PDB= 1mem |SIZE=350|CAPTION= <scene name='initialview01'>1mem</scene>, resolution 1.8&Aring;
|SITE= <scene name='pdbsite=CAT:Description+Not+Provided'>CAT</scene>
|SITE= <scene name='pdbsite=CAT:Description+Not+Provided'>CAT</scene>
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|LIGAND= <scene name='pdbligand=BZP:N1-CARBOXYPIPERAZINE'>BZP</scene> and <scene name='pdbligand=BNS:HYDROSULFONYLBENZENE'>BNS</scene>
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|LIGAND= <scene name='pdbligand=BNS:HYDROSULFONYLBENZENE'>BNS</scene>, <scene name='pdbligand=BZP:N1-CARBOXYPIPERAZINE'>BZP</scene>, <scene name='pdbligand=NFP:3-AMINO-5-PHENYLPENTANE'>NFP</scene>
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|ACTIVITY= [http://en.wikipedia.org/wiki/Cathepsin_K Cathepsin K], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.22.38 3.4.22.38]
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|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Cathepsin_K Cathepsin K], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.22.38 3.4.22.38] </span>
|GENE=
|GENE=
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|DOMAIN=
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|RELATEDENTRY=
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1mem FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1mem OCA], [http://www.ebi.ac.uk/pdbsum/1mem PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1mem RCSB]</span>
}}
}}
'''CRYSTAL STRUCTURE OF CATHEPSIN K COMPLEXED WITH A POTENT VINYL SULFONE INHIBITOR'''
'''CRYSTAL STRUCTURE OF CATHEPSIN K COMPLEXED WITH A POTENT VINYL SULFONE INHIBITOR'''
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==Disease==
 
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Known disease associated with this structure: Pycnodysostosis OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=601105 601105]]
 
==About this Structure==
==About this Structure==
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[[Category: Single protein]]
[[Category: Single protein]]
[[Category: Mcgrath, M E.]]
[[Category: Mcgrath, M E.]]
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[[Category: BNS]]
 
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[[Category: BZP]]
 
[[Category: complex (hydrolase/inhibitor)]]
[[Category: complex (hydrolase/inhibitor)]]
[[Category: cysteine]]
[[Category: cysteine]]
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[[Category: protease]]
[[Category: protease]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 12:42:32 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 22:15:11 2008''

Revision as of 19:15, 30 March 2008


PDB ID 1mem

Drag the structure with the mouse to rotate
, resolution 1.8Å
Sites:
Ligands: , ,
Activity: Cathepsin K, with EC number 3.4.22.38
Resources: FirstGlance, OCA, PDBsum, RCSB
Coordinates: save as pdb, mmCIF, xml



CRYSTAL STRUCTURE OF CATHEPSIN K COMPLEXED WITH A POTENT VINYL SULFONE INHIBITOR


About this Structure

1MEM is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Crystal structure of human cathepsin K complexed with a potent inhibitor., McGrath ME, Klaus JL, Barnes MG, Bromme D, Nat Struct Biol. 1997 Feb;4(2):105-9. PMID:9033587

Page seeded by OCA on Sun Mar 30 22:15:11 2008

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