2woq
From Proteopedia
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==PORPHOBILINOGEN SYNTHASE (HEMB) IN COMPLEX WITH 5-ACETAMIDO-4-OXOHEXANOIC ACID (ALAREMYCIN 2)== | ==PORPHOBILINOGEN SYNTHASE (HEMB) IN COMPLEX WITH 5-ACETAMIDO-4-OXOHEXANOIC ACID (ALAREMYCIN 2)== | ||
<StructureSection load='2woq' size='340' side='right' caption='[[2woq]], [[Resolution|resolution]] 1.75Å' scene=''> | <StructureSection load='2woq' size='340' side='right' caption='[[2woq]], [[Resolution|resolution]] 1.75Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2woq]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[2woq]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_aeruginosus"_(schroeter_1872)_trevisan_1885 "bacillus aeruginosus" (schroeter 1872) trevisan 1885]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WOQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WOQ FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=AYC:ALAREMYCIN+2'>AYC</scene>, <scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PE5:3,6,9,12,15,18,21,24-OCTAOXAHEXACOSAN-1-OL'>PE5</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=AYC:ALAREMYCIN+2'>AYC</scene>, <scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PE5:3,6,9,12,15,18,21,24-OCTAOXAHEXACOSAN-1-OL'>PE5</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2c18|2c18]], [[2c14|2c14]], [[1gzg|1gzg]], [[2c19|2c19]], [[1w5p|1w5p]], [[2c13|2c13]], [[1w5n|1w5n]], [[1w5q|1w5q]], [[1w54|1w54]], [[1w5m|1w5m]], [[1w5o|1w5o]], [[1w56|1w56]], [[2c16|2c16]], [[2c15|2c15]], [[1b4k|1b4k]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2c18|2c18]], [[2c14|2c14]], [[1gzg|1gzg]], [[2c19|2c19]], [[1w5p|1w5p]], [[2c13|2c13]], [[1w5n|1w5n]], [[1w5q|1w5q]], [[1w54|1w54]], [[1w5m|1w5m]], [[1w5o|1w5o]], [[1w56|1w56]], [[2c16|2c16]], [[2c15|2c15]], [[1b4k|1b4k]]</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Porphobilinogen_synthase Porphobilinogen synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.24 4.2.1.24] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Porphobilinogen_synthase Porphobilinogen synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.24 4.2.1.24] </span></td></tr> | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2woq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2woq OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2woq RCSB], [http://www.ebi.ac.uk/pdbsum/2woq PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2woq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2woq OCA], [http://pdbe.org/2woq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2woq RCSB], [http://www.ebi.ac.uk/pdbsum/2woq PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2woq ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
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<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
| - | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/ | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2woq ConSurf]. |
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
| + | <div class="pdbe-citations 2woq" style="background-color:#fffaf0;"></div> | ||
==See Also== | ==See Also== | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Porphobilinogen synthase]] | [[Category: Porphobilinogen synthase]] | ||
| - | [[Category: Pseudomonas aeruginosa]] | ||
[[Category: Awa, Y]] | [[Category: Awa, Y]] | ||
[[Category: Heinemann, I U]] | [[Category: Heinemann, I U]] | ||
Revision as of 12:03, 5 August 2016
PORPHOBILINOGEN SYNTHASE (HEMB) IN COMPLEX WITH 5-ACETAMIDO-4-OXOHEXANOIC ACID (ALAREMYCIN 2)
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Categories: Porphobilinogen synthase | Awa, Y | Heinemann, I U | Heinz, D W | Jahn, D | Jahn, M | Kobayashi, Y | Schubert, W D | Schulz, C | Wachi, M | Wang, Y G | Hemb | Heme biosynthesis | Inhibitor | Lyase | Lyase antibiotic complex | Lyase-antibiotic complex | Metal-binding | Porphyrin biosynthesis | Porpobilinogen synthase
