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3s2p

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==Crystal structure of CDK2 with a 2-aminopyrimidine compound==
==Crystal structure of CDK2 with a 2-aminopyrimidine compound==
<StructureSection load='3s2p' size='340' side='right' caption='[[3s2p]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
<StructureSection load='3s2p' size='340' side='right' caption='[[3s2p]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3s2p]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermomicrobium_roseum Thermomicrobium roseum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3S2P OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3S2P FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3s2p]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3S2P OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3S2P FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PMU:(3S,4S)-1-{3-[2-AMINO-6-(PROPAN-2-YL)PYRIMIDIN-4-YL]-4-HYDROXYPHENYL}PYRROLIDINE-3,4-DIOL'>PMU</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PMU:(3S,4S)-1-{3-[2-AMINO-6-(PROPAN-2-YL)PYRIMIDIN-4-YL]-4-HYDROXYPHENYL}PYRROLIDINE-3,4-DIOL'>PMU</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CDK2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=500 Thermomicrobium roseum])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CDK2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cyclin-dependent_kinase Cyclin-dependent kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.22 2.7.11.22] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cyclin-dependent_kinase Cyclin-dependent kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.22 2.7.11.22] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3s2p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3s2p OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3s2p RCSB], [http://www.ebi.ac.uk/pdbsum/3s2p PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3s2p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3s2p OCA], [http://pdbe.org/3s2p PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3s2p RCSB], [http://www.ebi.ac.uk/pdbsum/3s2p PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3s2p ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 3s2p" style="background-color:#fffaf0;"></div>
==See Also==
==See Also==
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*[[Cell division protein kinase 2|Cell division protein kinase 2]]
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*[[Cyclin-dependent kinase|Cyclin-dependent kinase]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Cyclin-dependent kinase]]
[[Category: Cyclin-dependent kinase]]
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[[Category: Thermomicrobium roseum]]
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[[Category: Human]]
[[Category: Jeong, S]]
[[Category: Jeong, S]]
[[Category: Kim, K H]]
[[Category: Kim, K H]]

Revision as of 13:41, 5 August 2016

Crystal structure of CDK2 with a 2-aminopyrimidine compound

3s2p, resolution 2.30Å

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