2y9h

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==STRUCTURE A OF CRISPR ENDORIBONUCLEASE CSE3 BOUND TO 19 NT RNA==
==STRUCTURE A OF CRISPR ENDORIBONUCLEASE CSE3 BOUND TO 19 NT RNA==
<StructureSection load='2y9h' size='340' side='right' caption='[[2y9h]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
<StructureSection load='2y9h' size='340' side='right' caption='[[2y9h]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2y9h]] is a 16 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Y9H OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2Y9H FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2y9h]] is a 16 chain structure with sequence from [http://en.wikipedia.org/wiki/Thet8 Thet8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Y9H OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2Y9H FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2y8y|2y8y]], [[1wj9|1wj9]], [[2y8w|2y8w]]</td></tr>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2y8y|2y8y]], [[1wj9|1wj9]], [[2y8w|2y8w]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2y9h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2y9h OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2y9h RCSB], [http://www.ebi.ac.uk/pdbsum/2y9h PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2y9h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2y9h OCA], [http://pdbe.org/2y9h PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2y9h RCSB], [http://www.ebi.ac.uk/pdbsum/2y9h PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2y9h ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/Q53WG9_THET8 Q53WG9_THET8]] CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Processes pre-crRNA into individual crRNA units, but may not actually undergo enzyme turnover, retaining the crRNA product. Generates a 2',3'-cyclic phosphodiester.<ref>PMID:21572442</ref> <ref>PMID:21572444</ref>
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[[http://www.uniprot.org/uniprot/CAS6_THET8 CAS6_THET8]] CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). This enzyme processes pre-crRNA into individual crRNA units, but may not actually undergo enzyme turnover, retaining the crRNA product (PubMed:21572442). Generates a 2',3'-cyclic phosphodiester.<ref>PMID:21572442</ref> <ref>PMID:21572444</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 2y9h" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Thermus thermophilus]]
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[[Category: Thet8]]
[[Category: Doudna, J A]]
[[Category: Doudna, J A]]
[[Category: Jinek, M]]
[[Category: Jinek, M]]

Revision as of 14:34, 5 August 2016

STRUCTURE A OF CRISPR ENDORIBONUCLEASE CSE3 BOUND TO 19 NT RNA

2y9h, resolution 2.50Å

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