4ezv
From Proteopedia
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==Crystal structure of the substrate binding domain of E.coli DnaK in complex with PR-bombesin in space group P21212== | ==Crystal structure of the substrate binding domain of E.coli DnaK in complex with PR-bombesin in space group P21212== | ||
<StructureSection load='4ezv' size='340' side='right' caption='[[4ezv]], [[Resolution|resolution]] 2.10Å' scene=''> | <StructureSection load='4ezv' size='340' side='right' caption='[[4ezv]], [[Resolution|resolution]] 2.10Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4ezv]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[4ezv]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EZV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4EZV FirstGlance]. <br> |
| - | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">b0014, dnaK, groP, grpF, JW0013, seg ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 | + | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">b0014, dnaK, groP, grpF, JW0013, seg ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI])</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ezv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ezv OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4ezv RCSB], [http://www.ebi.ac.uk/pdbsum/4ezv PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ezv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ezv OCA], [http://pdbe.org/4ezv PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4ezv RCSB], [http://www.ebi.ac.uk/pdbsum/4ezv PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4ezv ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
[[http://www.uniprot.org/uniprot/DNAK_ECOLI DNAK_ECOLI]] Plays an essential role in the initiation of phage lambda DNA replication, where it acts in an ATP-dependent fashion with the DnaJ protein to release lambda O and P proteins from the preprimosomal complex. DnaK is also involved in chromosomal DNA replication, possibly through an analogous interaction with the DnaA protein. Also participates actively in the response to hyperosmotic shock.[HAMAP-Rule:MF_00332] | [[http://www.uniprot.org/uniprot/DNAK_ECOLI DNAK_ECOLI]] Plays an essential role in the initiation of phage lambda DNA replication, where it acts in an ATP-dependent fashion with the DnaJ protein to release lambda O and P proteins from the preprimosomal complex. DnaK is also involved in chromosomal DNA replication, possibly through an analogous interaction with the DnaA protein. Also participates actively in the response to hyperosmotic shock.[HAMAP-Rule:MF_00332] | ||
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| + | ==See Also== | ||
| + | *[[Heat Shock Proteins|Heat Shock Proteins]] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Ecoli]] |
[[Category: Straeter, N]] | [[Category: Straeter, N]] | ||
[[Category: Zahn, M]] | [[Category: Zahn, M]] | ||
Revision as of 15:34, 5 August 2016
Crystal structure of the substrate binding domain of E.coli DnaK in complex with PR-bombesin in space group P21212
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