2z17

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==Crystal sturcture of PDZ domain from human Pleckstrin homology, Sec7==
==Crystal sturcture of PDZ domain from human Pleckstrin homology, Sec7==
<StructureSection load='2z17' size='340' side='right' caption='[[2z17]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
<StructureSection load='2z17' size='340' side='right' caption='[[2z17]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2z17]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z17 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2Z17 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2z17]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z17 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2Z17 FirstGlance]. <br>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2z17 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2z17 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2z17 RCSB], [http://www.ebi.ac.uk/pdbsum/2z17 PDBsum], [http://www.topsan.org/Proteins/RSGI/2z17 TOPSAN]</span></td></tr>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2z17 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2z17 OCA], [http://pdbe.org/2z17 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2z17 RCSB], [http://www.ebi.ac.uk/pdbsum/2z17 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2z17 ProSAT], [http://www.topsan.org/Proteins/RSGI/2z17 TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/PSCBP_HUMAN PSCBP_HUMAN]] By its binding to cytohesin-1 (CYTH1), it modifies activation of ARFs by CYTH1 and its precise function may be to sequester CYTH1 in the cytoplasm.
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[[http://www.uniprot.org/uniprot/CYTIP_HUMAN CYTIP_HUMAN]] By its binding to cytohesin-1 (CYTH1), it modifies activation of ARFs by CYTH1 and its precise function may be to sequester CYTH1 in the cytoplasm.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2z17 ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Human]]
[[Category: Kishishita, S]]
[[Category: Kishishita, S]]
[[Category: Murayama, K]]
[[Category: Murayama, K]]

Revision as of 18:08, 5 August 2016

Crystal sturcture of PDZ domain from human Pleckstrin homology, Sec7

2z17, resolution 2.70Å

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