2z17
From Proteopedia
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==Crystal sturcture of PDZ domain from human Pleckstrin homology, Sec7== | ==Crystal sturcture of PDZ domain from human Pleckstrin homology, Sec7== | ||
<StructureSection load='2z17' size='340' side='right' caption='[[2z17]], [[Resolution|resolution]] 2.70Å' scene=''> | <StructureSection load='2z17' size='340' side='right' caption='[[2z17]], [[Resolution|resolution]] 2.70Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
- | <table><tr><td colspan='2'>[[2z17]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[2z17]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z17 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2Z17 FirstGlance]. <br> |
- | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2z17 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2z17 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2z17 RCSB], [http://www.ebi.ac.uk/pdbsum/2z17 PDBsum], [http://www.topsan.org/Proteins/RSGI/2z17 TOPSAN]</span></td></tr> | + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2z17 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2z17 OCA], [http://pdbe.org/2z17 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2z17 RCSB], [http://www.ebi.ac.uk/pdbsum/2z17 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2z17 ProSAT], [http://www.topsan.org/Proteins/RSGI/2z17 TOPSAN]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
- | [[http://www.uniprot.org/uniprot/ | + | [[http://www.uniprot.org/uniprot/CYTIP_HUMAN CYTIP_HUMAN]] By its binding to cytohesin-1 (CYTH1), it modifies activation of ARFs by CYTH1 and its precise function may be to sequester CYTH1 in the cytoplasm. |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
- | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/ | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2z17 ConSurf]. |
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
- | [[Category: | + | [[Category: Human]] |
[[Category: Kishishita, S]] | [[Category: Kishishita, S]] | ||
[[Category: Murayama, K]] | [[Category: Murayama, K]] |
Revision as of 18:08, 5 August 2016
Crystal sturcture of PDZ domain from human Pleckstrin homology, Sec7
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