4hev

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==Clostridium Botulinum Serotype A Light Chain Inhibited By Adamantane Hydroxamate==
==Clostridium Botulinum Serotype A Light Chain Inhibited By Adamantane Hydroxamate==
<StructureSection load='4hev' size='340' side='right' caption='[[4hev]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
<StructureSection load='4hev' size='340' side='right' caption='[[4hev]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4hev]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Clostridium_botulinum Clostridium botulinum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HEV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4HEV FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4hev]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_botulinus"_van_ermengem_1896 "bacillus botulinus" van ermengem 1896]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HEV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4HEV FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=AXM:N-HYDROXY-2-[(3S,5S,7S)-TRICYCLO[3.3.1.1~3,7~]DEC-1-YL]ACETAMIDE'>AXM</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=AXM:N-HYDROXY-2-[(3S,5S,7S)-TRICYCLO[3.3.1.1~3,7~]DEC-1-YL]ACETAMIDE'>AXM</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">botA, atx, bna ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1491 Clostridium botulinum])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">botA, atx, bna ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1491 "Bacillus botulinus" van Ermengem 1896])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Bontoxilysin Bontoxilysin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.69 3.4.24.69] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Bontoxilysin Bontoxilysin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.69 3.4.24.69] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4hev FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hev OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4hev RCSB], [http://www.ebi.ac.uk/pdbsum/4hev PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4hev FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hev OCA], [http://pdbe.org/4hev PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4hev RCSB], [http://www.ebi.ac.uk/pdbsum/4hev PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4hev ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 4hev" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Botulinum neurotoxin|Botulinum neurotoxin]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Bacillus botulinus van ermengem 1896]]
[[Category: Bontoxilysin]]
[[Category: Bontoxilysin]]
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[[Category: Clostridium botulinum]]
 
[[Category: Allen, K N]]
[[Category: Allen, K N]]
[[Category: Silvaggi, N R]]
[[Category: Silvaggi, N R]]
[[Category: Hydrolase-hydrolase inhibitor complex]]
[[Category: Hydrolase-hydrolase inhibitor complex]]
[[Category: Zn2+-dependent metalloprotease]]
[[Category: Zn2+-dependent metalloprotease]]

Revision as of 18:36, 5 August 2016

Clostridium Botulinum Serotype A Light Chain Inhibited By Adamantane Hydroxamate

4hev, resolution 2.50Å

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