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3lm5
From Proteopedia
(Difference between revisions)
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==Crystal Structure of human Serine/Threonine Kinase 17B (STK17B) in complex with Quercetin== | ==Crystal Structure of human Serine/Threonine Kinase 17B (STK17B) in complex with Quercetin== | ||
<StructureSection load='3lm5' size='340' side='right' caption='[[3lm5]], [[Resolution|resolution]] 2.29Å' scene=''> | <StructureSection load='3lm5' size='340' side='right' caption='[[3lm5]], [[Resolution|resolution]] 2.29Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3lm5]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[3lm5]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LM5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3LM5 FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=QUE:3,5,7,3,4-PENTAHYDROXYFLAVONE'>QUE</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=QUE:3,5,7,3,4-PENTAHYDROXYFLAVONE'>QUE</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3eha|3eha]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3eha|3eha]]</td></tr> | ||
| - | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">DRAK2, STK17B ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">DRAK2, STK17B ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> |
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr> | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3lm5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3lm5 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3lm5 RCSB], [http://www.ebi.ac.uk/pdbsum/3lm5 PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3lm5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3lm5 OCA], [http://pdbe.org/3lm5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3lm5 RCSB], [http://www.ebi.ac.uk/pdbsum/3lm5 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3lm5 ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
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<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
| - | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/ | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3lm5 ConSurf]. |
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Human]] |
[[Category: Non-specific serine/threonine protein kinase]] | [[Category: Non-specific serine/threonine protein kinase]] | ||
[[Category: Arrowsmith, C H]] | [[Category: Arrowsmith, C H]] | ||
Revision as of 19:45, 5 August 2016
Crystal Structure of human Serine/Threonine Kinase 17B (STK17B) in complex with Quercetin
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Categories: Human | Non-specific serine/threonine protein kinase | Arrowsmith, C H | Bountra, C | Carpenter, L | Chaikuad, A | Delft, F von | Edwards, A | Fedorov, O | Filippakopoulos, P | Hapka, E | Knapp, S | Phillips, C | Pike, A C.W | Rellos, P | Structural genomic | Soundararajan, M | Ugochukwu, E | Vollmar, M | Wang, J | Weigelt, J | Apoptosis | Atp-binding | Dap kinase related apoptosis-inducing protein kinase 2 | Death-associated protein kinase-related 2 | Drak2 | Kinase | Nucleotide-binding | Nucleus | Phosphoprotein | Serine/threonine kinase 17b | Serine/threonine-protein kinase | Sgc | Stk17b | Transferase
