4ght

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==Crystal structure of EV71 3C proteinase in complex with AG7088==
==Crystal structure of EV71 3C proteinase in complex with AG7088==
<StructureSection load='4ght' size='340' side='right' caption='[[4ght]], [[Resolution|resolution]] 1.96&Aring;' scene=''>
<StructureSection load='4ght' size='340' side='right' caption='[[4ght]], [[Resolution|resolution]] 1.96&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4ght]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Enterovirus_a71 Enterovirus a71]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GHT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4GHT FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4ght]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Ev-71 Ev-71]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GHT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4GHT FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=AG7:4-{2-(4-FLUORO-BENZYL)-6-METHYL-5-[(5-METHYL-ISOXAZOLE-3-CARBONYL)-AMINO]-4-OXO-HEPTANOYLAMINO}-5-(2-OXO-PYRROLIDIN-3-YL)-PENTANOIC+ACID+ETHYL+ESTER'>AG7</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=AG7:4-{2-(4-FLUORO-BENZYL)-6-METHYL-5-[(5-METHYL-ISOXAZOLE-3-CARBONYL)-AMINO]-4-OXO-HEPTANOYLAMINO}-5-(2-OXO-PYRROLIDIN-3-YL)-PENTANOIC+ACID+ETHYL+ESTER'>AG7</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4ghq|4ghq]], [[4ghv|4ghv]], [[4ghx|4ghx]], [[4ghy|4ghy]], [[4ghz|4ghz]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4ghq|4ghq]], [[4ghv|4ghv]], [[4ghx|4ghx]], [[4ghy|4ghy]], [[4ghz|4ghz]]</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Picornain_3C Picornain 3C], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.22.28 3.4.22.28] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Picornain_3C Picornain 3C], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.22.28 3.4.22.28] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ght FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ght OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4ght RCSB], [http://www.ebi.ac.uk/pdbsum/4ght PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ght FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ght OCA], [http://pdbe.org/4ght PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4ght RCSB], [http://www.ebi.ac.uk/pdbsum/4ght PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4ght ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 4ght" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Proteinase|Proteinase]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Enterovirus a71]]
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[[Category: Ev-71]]
[[Category: Picornain 3C]]
[[Category: Picornain 3C]]
[[Category: Cai, Q]]
[[Category: Cai, Q]]

Revision as of 21:23, 5 August 2016

Crystal structure of EV71 3C proteinase in complex with AG7088

4ght, resolution 1.96Å

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