4ajd

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==Identification and structural characterization of PDE10 fragment inhibitors==
==Identification and structural characterization of PDE10 fragment inhibitors==
<StructureSection load='4ajd' size='340' side='right' caption='[[4ajd]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
<StructureSection load='4ajd' size='340' side='right' caption='[[4ajd]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4ajd]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AJD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4AJD FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4ajd]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AJD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4AJD FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=F04:2-ETHYL-4-METHYL-PHTHALAZIN-1-ONE'>F04</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=F04:2-ETHYL-4-METHYL-PHTHALAZIN-1-ONE'>F04</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1lrb|1lrb]], [[2wey|2wey]], [[2y0j|2y0j]], [[4ael|4ael]], [[4ajf|4ajf]], [[4ajg|4ajg]], [[4ajm|4ajm]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1lrb|1lrb]], [[2wey|2wey]], [[2y0j|2y0j]], [[4ael|4ael]], [[4ajf|4ajf]], [[4ajg|4ajg]], [[4ajm|4ajm]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ajd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ajd OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4ajd RCSB], [http://www.ebi.ac.uk/pdbsum/4ajd PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ajd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ajd OCA], [http://pdbe.org/4ajd PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4ajd RCSB], [http://www.ebi.ac.uk/pdbsum/4ajd PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4ajd ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Human]]
[[Category: Aharony, D]]
[[Category: Aharony, D]]
[[Category: Akerud, T]]
[[Category: Akerud, T]]

Revision as of 22:22, 5 August 2016

Identification and structural characterization of PDE10 fragment inhibitors

4ajd, resolution 2.30Å

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