1n5b

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|ACTIVITY=
|ACTIVITY=
|GENE= YERA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=630 Yersinia enterocolitica])
|GENE= YERA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=630 Yersinia enterocolitica])
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|DOMAIN=
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|RELATEDENTRY=[[1jya|1JYA]], [[1k6z|1K6Z]], [[1l2w|1L2W]], [[1md1|1MD1]]
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1n5b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1n5b OCA], [http://www.ebi.ac.uk/pdbsum/1n5b PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1n5b RCSB]</span>
}}
}}
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[[Category: yersinia enterocolitica]]
[[Category: yersinia enterocolitica]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 12:52:19 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 22:25:33 2008''

Revision as of 19:25, 30 March 2008


PDB ID 1n5b

Drag the structure with the mouse to rotate
, resolution 2.00Å
Gene: YERA (Yersinia enterocolitica)
Related: 1JYA, 1K6Z, 1L2W, 1MD1


Resources: FirstGlance, OCA, PDBsum, RCSB
Coordinates: save as pdb, mmCIF, xml



Crystal Structure Of The Yersinia enterocolitica Molecular Chaperone Syce


Overview

The crystal structure of the Yersinia enterocolitica molecular-chaperone protein SycE, which specifically binds the YopE protein, has been solved to 2.0 A resolution by molecular replacement. The crystal contains two SycE dimers per asymmetric unit; a novel feature of this crystal, when compared with closely related SycE structures, is a well ordered carboxy-terminal peptide in one protomer of each dimer. The peptide binds a hydrophobic patch of a neighboring molecule in a manner similar to that seen in a SycE-YopE chaperone-target complex, suggestive of low-affinity 'self-binding' through which the carboxy-terminal peptide might suppress counterproductive interactions with non-target proteins in vivo.

About this Structure

1N5B is a Single protein structure of sequence from Yersinia enterocolitica. This structure supersedes the now removed PDB entry 1MD1. Full crystallographic information is available from OCA.

Reference

Structure of the Yersinia enterocolitica molecular-chaperone protein SycE., Trame CB, McKay DB, Acta Crystallogr D Biol Crystallogr. 2003 Feb;59(Pt 2):389-92. Epub 2003, Jan 23. PMID:12554962

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