This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
4doh
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| + | |||
==IL20/IL201/IL20R2 Ternary Complex== | ==IL20/IL201/IL20R2 Ternary Complex== | ||
<StructureSection load='4doh' size='340' side='right' caption='[[4doh]], [[Resolution|resolution]] 2.80Å' scene=''> | <StructureSection load='4doh' size='340' side='right' caption='[[4doh]], [[Resolution|resolution]] 2.80Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4doh]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[4doh]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DOH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4DOH FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr> | ||
| - | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">IL20, ZCYTO10, UNQ852/PRO1801 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">IL20, ZCYTO10, UNQ852/PRO1801 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN]), IL20RB, DIRS1, UNQ557/PRO1114 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN]), IL20RA, UNQ681/PRO1315 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4doh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4doh OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4doh RCSB], [http://www.ebi.ac.uk/pdbsum/4doh PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4doh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4doh OCA], [http://pdbe.org/4doh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4doh RCSB], [http://www.ebi.ac.uk/pdbsum/4doh PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4doh ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[http://www.uniprot.org/uniprot/IL20_HUMAN IL20_HUMAN]] Cytokine that may be involved in epidermal function and psoriasis. Acts through STAT3. | + | [[http://www.uniprot.org/uniprot/IL20_HUMAN IL20_HUMAN]] Cytokine that may be involved in epidermal function and psoriasis. Acts through STAT3. [[http://www.uniprot.org/uniprot/I20RA_HUMAN I20RA_HUMAN]] The IL20RA/IL20RB dimer is a receptor for IL19, IL20 and IL24. The IL20RA/IL10RB dimer is a receptor for IL26. [[http://www.uniprot.org/uniprot/I20RB_HUMAN I20RB_HUMAN]] The IL20RA/IL20RB dimer is a receptor for IL19, IL20 and IL24. The IL22RA1/IL20RB dimer is a receptor for IL20 and IL24. |
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
| Line 17: | Line 18: | ||
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
| + | <div class="pdbe-citations 4doh" style="background-color:#fffaf0;"></div> | ||
==See Also== | ==See Also== | ||
| Line 25: | Line 27: | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Human]] |
[[Category: Logsdon, N J]] | [[Category: Logsdon, N J]] | ||
[[Category: Walter, M R]] | [[Category: Walter, M R]] | ||
Revision as of 23:04, 5 August 2016
IL20/IL201/IL20R2 Ternary Complex
| |||||||||||
