This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
2wu4
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| + | |||
==CRYSTAL STRUCTURE OF MOUSE ACETYLCHOLINESTERASE IN COMPLEX WITH FENAMIPHOS AND ORTHO-7== | ==CRYSTAL STRUCTURE OF MOUSE ACETYLCHOLINESTERASE IN COMPLEX WITH FENAMIPHOS AND ORTHO-7== | ||
<StructureSection load='2wu4' size='340' side='right' caption='[[2wu4]], [[Resolution|resolution]] 2.40Å' scene=''> | <StructureSection load='2wu4' size='340' side='right' caption='[[2wu4]], [[Resolution|resolution]] 2.40Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2wu4]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[2wu4]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WU4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WU4 FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HBP:1,7-HEPTYLENE-BIS-N,N-SYN-2-PYRIDINIUMALDOXIME'>HBP</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=P6G:HEXAETHYLENE+GLYCOL'>P6G</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HBP:1,7-HEPTYLENE-BIS-N,N-SYN-2-PYRIDINIUMALDOXIME'>HBP</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=P6G:HEXAETHYLENE+GLYCOL'>P6G</scene></td></tr> | ||
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=SXE:O-{(S)-ETHOXY[(1-METHYLETHYL)AMINO]PHOSPHORYL}-L-SERINE'>SXE</scene></td></tr> | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=SXE:O-{(S)-ETHOXY[(1-METHYLETHYL)AMINO]PHOSPHORYL}-L-SERINE'>SXE</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2jgh|2jgh]], [[2whq|2whq]], [[1mah|1mah]], [[2ha6|2ha6]], [[1maa|1maa]], [[2c0q|2c0q]], [[2jgg|2jgg]], [[2jgl|2jgl]], [[1q84|1q84]], [[2jgm|2jgm]], [[2jge|2jge]], [[1q83|1q83]], [[2wls|2wls]], [[1c2b|1c2b]], [[2ha3|2ha3]], [[2ha0|2ha0]], [[2jey|2jey]], [[2jgi|2jgi]], [[1n5r|1n5r]], [[2jgj|2jgj]], [[1j06|1j06]], [[2jf0|2jf0]], [[2c0p|2c0p]], [[2h9y|2h9y]], [[2whr|2whr]], [[1n5m|1n5m]], [[2ha5|2ha5]], [[2ha2|2ha2]], [[2whp|2whp]], [[2jez|2jez]], [[2jgk|2jgk]], [[1ku6|1ku6]], [[2ha4|2ha4]], [[1j07|1j07]], [[2jgf|2jgf]], [[2ha7|2ha7]], [[1c2o|1c2o]], [[2wu3|2wu3]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2jgh|2jgh]], [[2whq|2whq]], [[1mah|1mah]], [[2ha6|2ha6]], [[1maa|1maa]], [[2c0q|2c0q]], [[2jgg|2jgg]], [[2jgl|2jgl]], [[1q84|1q84]], [[2jgm|2jgm]], [[2jge|2jge]], [[1q83|1q83]], [[2wls|2wls]], [[1c2b|1c2b]], [[2ha3|2ha3]], [[2ha0|2ha0]], [[2jey|2jey]], [[2jgi|2jgi]], [[1n5r|1n5r]], [[2jgj|2jgj]], [[1j06|1j06]], [[2jf0|2jf0]], [[2c0p|2c0p]], [[2h9y|2h9y]], [[2whr|2whr]], [[1n5m|1n5m]], [[2ha5|2ha5]], [[2ha2|2ha2]], [[2whp|2whp]], [[2jez|2jez]], [[2jgk|2jgk]], [[1ku6|1ku6]], [[2ha4|2ha4]], [[1j07|1j07]], [[2jgf|2jgf]], [[2ha7|2ha7]], [[1c2o|1c2o]], [[2wu3|2wu3]]</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Acetylcholinesterase Acetylcholinesterase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.7 3.1.1.7] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Acetylcholinesterase Acetylcholinesterase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.7 3.1.1.7] </span></td></tr> | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wu4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wu4 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2wu4 RCSB], [http://www.ebi.ac.uk/pdbsum/2wu4 PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wu4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wu4 OCA], [http://pdbe.org/2wu4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2wu4 RCSB], [http://www.ebi.ac.uk/pdbsum/2wu4 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2wu4 ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| Line 19: | Line 20: | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
| - | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/ | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2wu4 ConSurf]. |
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
| Line 29: | Line 30: | ||
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
| + | <div class="pdbe-citations 2wu4" style="background-color:#fffaf0;"></div> | ||
==See Also== | ==See Also== | ||
*[[Acetylcholinesterase|Acetylcholinesterase]] | *[[Acetylcholinesterase|Acetylcholinesterase]] | ||
| + | *[[3D structures of acetylcholinesterase|3D structures of acetylcholinesterase]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
| Line 37: | Line 40: | ||
</StructureSection> | </StructureSection> | ||
[[Category: Acetylcholinesterase]] | [[Category: Acetylcholinesterase]] | ||
| - | [[Category: | + | [[Category: Lk3 transgenic mice]] |
[[Category: Artursson, E]] | [[Category: Artursson, E]] | ||
[[Category: Ekstrom, F]] | [[Category: Ekstrom, F]] | ||
Revision as of 23:23, 5 August 2016
CRYSTAL STRUCTURE OF MOUSE ACETYLCHOLINESTERASE IN COMPLEX WITH FENAMIPHOS AND ORTHO-7
| |||||||||||
