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4as0

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==Cyclometalated Phthalimides as Protein Kinase Inhibitors==
==Cyclometalated Phthalimides as Protein Kinase Inhibitors==
<StructureSection load='4as0' size='340' side='right' caption='[[4as0]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
<StructureSection load='4as0' size='340' side='right' caption='[[4as0]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4as0]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AS0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4AS0 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4as0]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AS0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4AS0 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=RPS:PHTALIMIDE-RUTHENIUM+COMPLEX'>RPS</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=RPS:PHTALIMIDE-RUTHENIUM+COMPLEX'>RPS</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1xqz|1xqz]], [[1xr1|1xr1]], [[1xws|1xws]], [[1yhs|1yhs]], [[1yi3|1yi3]], [[1yi4|1yi4]], [[1ywv|1ywv]], [[1yxs|1yxs]], [[1yxt|1yxt]], [[1yxu|1yxu]], [[1yxv|1yxv]], [[1yxx|1yxx]], [[2bik|2bik]], [[2bil|2bil]], [[2bzh|2bzh]], [[2bzi|2bzi]], [[2bzj|2bzj]], [[2bzk|2bzk]], [[2c3i|2c3i]], [[2j2i|2j2i]], [[2xix|2xix]], [[2xiy|2xiy]], [[2xiz|2xiz]], [[2xj0|2xj0]], [[2xj1|2xj1]], [[2xj2|2xj2]], [[4a7c|4a7c]], [[4alu|4alu]], [[4alv|4alv]], [[4alw|4alw]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1xqz|1xqz]], [[1xr1|1xr1]], [[1xws|1xws]], [[1yhs|1yhs]], [[1yi3|1yi3]], [[1yi4|1yi4]], [[1ywv|1ywv]], [[1yxs|1yxs]], [[1yxt|1yxt]], [[1yxu|1yxu]], [[1yxv|1yxv]], [[1yxx|1yxx]], [[2bik|2bik]], [[2bil|2bil]], [[2bzh|2bzh]], [[2bzi|2bzi]], [[2bzj|2bzj]], [[2bzk|2bzk]], [[2c3i|2c3i]], [[2j2i|2j2i]], [[2xix|2xix]], [[2xiy|2xiy]], [[2xiz|2xiz]], [[2xj0|2xj0]], [[2xj1|2xj1]], [[2xj2|2xj2]], [[4a7c|4a7c]], [[4alu|4alu]], [[4alv|4alv]], [[4alw|4alw]]</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4as0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4as0 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4as0 RCSB], [http://www.ebi.ac.uk/pdbsum/4as0 PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4as0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4as0 OCA], [http://pdbe.org/4as0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4as0 RCSB], [http://www.ebi.ac.uk/pdbsum/4as0 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4as0 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 4as0" style="background-color:#fffaf0;"></div>
==See Also==
==See Also==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Human]]
[[Category: Non-specific serine/threonine protein kinase]]
[[Category: Non-specific serine/threonine protein kinase]]
[[Category: Blanck, S]]
[[Category: Blanck, S]]

Revision as of 23:34, 5 August 2016

Cyclometalated Phthalimides as Protein Kinase Inhibitors

4as0, resolution 2.30Å

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