Response regulator
From Proteopedia
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'''Response regulators''' (RR) are part of the two-component signal transduction systems which enable bacteria to sense and respond to a wide range of environments. | '''Response regulators''' (RR) are part of the two-component signal transduction systems which enable bacteria to sense and respond to a wide range of environments. | ||
| - | Two-component RR is a complex of histidine kinase (sensor protein SP) and RR. The RR act as phosphorylation-activated switches. Most RR consist of N terminal | + | Two-component RR is a complex of histidine kinase (sensor protein SP) and RR. The RR act as phosphorylation-activated switches. Most RR consist of N terminal which is the signal receiving domain and C terminal which is the DNA-binding domain. |
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| - | + | *'''RR CheY''' is a chemotaxis response regulator in bacteria<ref>PMID:14563873</ref>. <br /> | |
| - | + | *'''RR Spo0''' is the sporulation response regulator<ref>PMID:12829280</ref>. <br /> | |
| - | + | *'''RR PleD''' is required in loss of motility<ref>PMID:7592388</ref>. For details see [[PleD activation]], [[PleD allosteric product inhibition]], [[PleD catalysis]] and [[Response regulator PLED in complex with C-di-GMP]]<br /> | |
| - | + | *'''RR PhoP''' is important for survival under conditions of macrophage-induced stress<ref>PMID:7592388</ref>. For details see [[PhoP Regulatory Domain]] and [[PhoP-PhoQ]]<br /> | |
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For photosynthetic apparatus RR:<br /> | For photosynthetic apparatus RR:<br /> | ||
*[[PrrA in Rhodobacter sphaeroides]] <br /> | *[[PrrA in Rhodobacter sphaeroides]] <br /> | ||
Revision as of 06:44, 7 August 2016
Response regulators (RR) are part of the two-component signal transduction systems which enable bacteria to sense and respond to a wide range of environments. Two-component RR is a complex of histidine kinase (sensor protein SP) and RR. The RR act as phosphorylation-activated switches. Most RR consist of N terminal which is the signal receiving domain and C terminal which is the DNA-binding domain.
- RR CheY is a chemotaxis response regulator in bacteria[1].
- RR Spo0 is the sporulation response regulator[2].
- RR PleD is required in loss of motility[3]. For details see PleD activation, PleD allosteric product inhibition, PleD catalysis and Response regulator PLED in complex with C-di-GMP
- RR PhoP is important for survival under conditions of macrophage-induced stress[4]. For details see PhoP Regulatory Domain and PhoP-PhoQ
For photosynthetic apparatus RR:
For WspR RR:
- WspR.
3D Structures of response regulator
Updated on 07-August-2016
Proteopedia Page Contributors and Editors (what is this?)
Michal Harel, Joel L. Sussman, Alexander Berchansky, Jaime Prilusky
