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5exi
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of M. tuberculosis lipoyl synthase at 2.28 A resolution== | |
| - | + | <StructureSection load='5exi' size='340' side='right' caption='[[5exi]], [[Resolution|resolution]] 2.28Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5exi]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5EXI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5EXI FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DTV:(2S,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL'>DTV</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene></td></tr> | |
| - | [[Category: | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5exj|5exj]], [[5exk|5exk]]</td></tr> |
| + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Lipoyl_synthase Lipoyl synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.8.1.8 2.8.1.8] </span></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5exi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5exi OCA], [http://pdbe.org/5exi PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5exi RCSB], [http://www.ebi.ac.uk/pdbsum/5exi PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5exi ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/LIPA_MYCTU LIPA_MYCTU]] Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Lipoyl synthase]] | ||
| + | [[Category: Booker, S J]] | ||
| + | [[Category: Drennan, C L]] | ||
| + | [[Category: Goldman, P J]] | ||
| + | [[Category: Lanz, N D]] | ||
| + | [[Category: Lee, K H]] | ||
| + | [[Category: McLaughlin, M I]] | ||
| + | [[Category: Adomet radical]] | ||
| + | [[Category: Auxiliary iron-sulfur cluster]] | ||
| + | [[Category: Radical sam]] | ||
| + | [[Category: Sulfur insertion]] | ||
| + | [[Category: Transferase]] | ||
Revision as of 16:23, 10 August 2016
Crystal structure of M. tuberculosis lipoyl synthase at 2.28 A resolution
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