5ik8
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Laminin A2LG45 I-form, G6/7 bound.== | |
| - | + | <StructureSection load='5ik8' size='340' side='right' caption='[[5ik8]], [[Resolution|resolution]] 2.00Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5ik8]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5IK8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5IK8 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=4MU:7-HYDROXY-4-METHYL-2H-CHROMEN-2-ONE'>4MU</scene>, <scene name='pdbligand=BDP:BETA-D-GLUCOPYRANURONIC+ACID'>BDP</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FLC:CITRATE+ANION'>FLC</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=XYS:XYLOPYRANOSE'>XYS</scene></td></tr> | |
| - | [[Category: | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5ik7|5ik7]]</td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ik8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ik8 OCA], [http://pdbe.org/5ik8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ik8 RCSB], [http://www.ebi.ac.uk/pdbsum/5ik8 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ik8 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Disease == | ||
| + | [[http://www.uniprot.org/uniprot/LAMA2_MOUSE LAMA2_MOUSE]] Note=Defects in Lama2 are a cause of murine muscular dystrophy (dy2J). | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/LAMA2_MOUSE LAMA2_MOUSE]] Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Briggs, D C]] | ||
| + | [[Category: Campbell, K P]] | ||
| + | [[Category: Hohenester, E]] | ||
| + | [[Category: Extracellular matrix]] | ||
| + | [[Category: Lg domain]] | ||
| + | [[Category: Ligand binding]] | ||
| + | [[Category: Structural protein]] | ||
Revision as of 16:26, 10 August 2016
Laminin A2LG45 I-form, G6/7 bound.
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