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5jic

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'''Unreleased structure'''
 
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The entry 5jic is ON HOLD until Paper Publication
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==Staphylococcus aureus Type II pantothenate kinase in complex with a pantothenate analog==
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<StructureSection load='5jic' size='340' side='right' caption='[[5jic]], [[Resolution|resolution]] 1.40&Aring;' scene=''>
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Authors: Hughes, S.J., Antoshchenko, T., Mottaghi, K., Barnard, L., Strauss, E., Park, H.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5jic]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5JIC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5JIC FirstGlance]. <br>
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Description: Staphylococcus aureus Type II pantothenate kinase in complex with a pantothenate analog
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=N7E:N~3~-[(2R)-2-HYDROXY-3,3-DIMETHYL-4-(PHOSPHONOOXY)BUTANOYL]-N-(5-METHOXYPENTYL)-BETA-ALANINAMIDE'>N7E</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Pantothenate_kinase Pantothenate kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.33 2.7.1.33] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5jic FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5jic OCA], [http://pdbe.org/5jic PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5jic RCSB], [http://www.ebi.ac.uk/pdbsum/5jic PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5jic ProSAT]</span></td></tr>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/COAW_STAAW COAW_STAAW]] Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity).
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__TOC__
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</StructureSection>
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[[Category: Pantothenate kinase]]
[[Category: Antoshchenko, T]]
[[Category: Antoshchenko, T]]
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[[Category: Barnard, L]]
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[[Category: Hughes, S J]]
[[Category: Mottaghi, K]]
[[Category: Mottaghi, K]]
[[Category: Park, H]]
[[Category: Park, H]]
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[[Category: Barnard, L]]
 
[[Category: Strauss, E]]
[[Category: Strauss, E]]
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[[Category: Hughes, S.J]]
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[[Category: Antimicrobial]]
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[[Category: Inhibitor]]
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[[Category: Pantothenamide]]
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[[Category: Transferase-transferase inhibitor complex]]

Revision as of 16:27, 10 August 2016

Staphylococcus aureus Type II pantothenate kinase in complex with a pantothenate analog

5jic, resolution 1.40Å

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