5jne
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==E2-SUMO-Siz1 E3-SUMO-PCNA complex== | |
| - | + | <StructureSection load='5jne' size='340' side='right' caption='[[5jne]], [[Resolution|resolution]] 2.85Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5jne]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5JNE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5JNE FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=6LN:ETHANE-1,2-DITHIOL'>6LN</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5jne FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5jne OCA], [http://pdbe.org/5jne PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5jne RCSB], [http://www.ebi.ac.uk/pdbsum/5jne PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5jne ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/PCNA_YEAST PCNA_YEAST]] This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand. Involved in DNA repair.<ref>PMID:11545742</ref> <ref>PMID:12226657</ref> [[http://www.uniprot.org/uniprot/SIZ1_YEAST SIZ1_YEAST]] Acts as an E3 ligase mediating SUMO/Smt3 attachment to septins and PCNA. May be involved in chromosome maintenance.<ref>PMID:11572779</ref> <ref>PMID:11587849</ref> <ref>PMID:11333221</ref> <ref>PMID:11577116</ref> <ref>PMID:12226657</ref> [[http://www.uniprot.org/uniprot/SMT3_YEAST SMT3_YEAST]] Not known; suppressor of MIF2 mutations. [[http://www.uniprot.org/uniprot/UBC9_YEAST UBC9_YEAST]] E2 ubiquitin-like--protein ligase mediating SUMO/Smt3 attachment to septins and PCNA. Seems to be involved in degradation of S- (CLB5) and M-phase cyclins (CLB2).<ref>PMID:9341106</ref> <ref>PMID:11572779</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Lima, C D]] | ||
| + | [[Category: Streich, F C]] | ||
| + | [[Category: E2 conjugating enzyme]] | ||
| + | [[Category: E3 ligase]] | ||
| + | [[Category: Ligase-signaling protein complex]] | ||
| + | [[Category: Substrate complex]] | ||
| + | [[Category: Sumo]] | ||
| + | [[Category: Ubiquitin]] | ||
| + | [[Category: Ubiquitin-like]] | ||
Revision as of 16:27, 10 August 2016
E2-SUMO-Siz1 E3-SUMO-PCNA complex
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