5jpa
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Hexameric HIV-1 CA H12Y mutant== | |
| - | + | <StructureSection load='5jpa' size='340' side='right' caption='[[5jpa]], [[Resolution|resolution]] 1.70Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5jpa]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5JPA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5JPA FirstGlance]. <br> | |
| - | + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5jpa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5jpa OCA], [http://pdbe.org/5jpa PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5jpa RCSB], [http://www.ebi.ac.uk/pdbsum/5jpa PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5jpa ProSAT]</span></td></tr> | |
| - | [[Category: | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/GAG_HV1N5 GAG_HV1N5]] Matrix protein p17 targets Gag and Gag-Pol polyproteins to the plasma membrane via a multipartite membrane binding signal, that includes its myristoylated N-terminus. Also mediates nuclear localization of the preintegration complex. Implicated in the release from host cell mediated by Vpu. Capsid protein p24 forms the conical core of the virus that encapsulates the genomic RNA-nucleocapsid complex. Nucleocapsid protein p7 encapsulates and protects viral dimeric unspliced (genomic) RNA. Binds these RNAs through its zinc fingers. p6-gag plays a role in budding of the assembled particle by interacting with the host class E VPS proteins TSG101 and PDCD6IP/AIP1 (By similarity). | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Jacques, D A]] | ||
| + | [[Category: James, L C]] | ||
| + | [[Category: Capsid]] | ||
| + | [[Category: Viral protein]] | ||
Revision as of 16:27, 10 August 2016
Hexameric HIV-1 CA H12Y mutant
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