3sh3
From Proteopedia
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==Crystal structure of a pro-inflammatory lectin from the seeds of Dioclea wilsonii STANDL== | ==Crystal structure of a pro-inflammatory lectin from the seeds of Dioclea wilsonii STANDL== | ||
<StructureSection load='3sh3' size='340' side='right' caption='[[3sh3]], [[Resolution|resolution]] 2.30Å' scene=''> | <StructureSection load='3sh3' size='340' side='right' caption='[[3sh3]], [[Resolution|resolution]] 2.30Å' scene=''> | ||
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=A3B:D-VINYLGLYCINE'>A3B</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=XMM:(2R,3S,4S,5S,6R)-2-(5-BROMO-4-CHLORO-1H-INDOL-3-YLOXY)-TETRAHYDRO-6-(HYDROXYMETHYL)-2H-PYRAN-3,4,5-TRIOL'>XMM</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=A3B:D-VINYLGLYCINE'>A3B</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=XMM:(2R,3S,4S,5S,6R)-2-(5-BROMO-4-CHLORO-1H-INDOL-3-YLOXY)-TETRAHYDRO-6-(HYDROXYMETHYL)-2H-PYRAN-3,4,5-TRIOL'>XMM</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3rrd|3rrd]], [[3rs6|3rs6]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3rrd|3rrd]], [[3rs6|3rs6]]</td></tr> | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3sh3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3sh3 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3sh3 RCSB], [http://www.ebi.ac.uk/pdbsum/3sh3 PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3sh3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3sh3 OCA], [http://pdbe.org/3sh3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3sh3 RCSB], [http://www.ebi.ac.uk/pdbsum/3sh3 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3sh3 ProSAT]</span></td></tr> |
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/LECA_DIOWI LECA_DIOWI]] D-mannose/D-glucose-binding lectin with hemagglutinating activity towards rabbit and human erythrocytes. In rats, elicits an acute inflammatory response by inducing neutrophil migration and induces dose-dependent paw edema.<ref>PMID:21694673</ref> <ref>PMID:21924319</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
| + | <div class="pdbe-citations 3sh3" style="background-color:#fffaf0;"></div> | ||
== References == | == References == | ||
<references/> | <references/> | ||
Revision as of 07:29, 11 August 2016
Crystal structure of a pro-inflammatory lectin from the seeds of Dioclea wilsonii STANDL
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