1nik

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|PDB= 1nik |SIZE=350|CAPTION= <scene name='initialview01'>1nik</scene>, resolution 4.10&Aring;
|PDB= 1nik |SIZE=350|CAPTION= <scene name='initialview01'>1nik</scene>, resolution 4.10&Aring;
|SITE=
|SITE=
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|LIGAND= <scene name='pdbligand=ZN:ZINC ION'>ZN</scene>
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|LIGAND= <scene name='pdbligand=UNK:UNKNOWN'>UNK</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>
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|ACTIVITY= [http://en.wikipedia.org/wiki/DNA-directed_RNA_polymerase DNA-directed RNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.6 2.7.7.6]
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|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA-directed_RNA_polymerase DNA-directed RNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.6 2.7.7.6] </span>
|GENE=
|GENE=
 +
|DOMAIN=
 +
|RELATEDENTRY=
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1nik FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nik OCA], [http://www.ebi.ac.uk/pdbsum/1nik PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1nik RCSB]</span>
}}
}}
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[[Category: Bushnell, D A.]]
[[Category: Bushnell, D A.]]
[[Category: Kornberg, R D.]]
[[Category: Kornberg, R D.]]
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[[Category: ZN]]
 
[[Category: transferase]]
[[Category: transferase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 12:57:24 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 22:30:51 2008''

Revision as of 19:30, 30 March 2008


PDB ID 1nik

Drag the structure with the mouse to rotate
, resolution 4.10Å
Ligands: ,
Activity: DNA-directed RNA polymerase, with EC number 2.7.7.6
Resources: FirstGlance, OCA, PDBsum, RCSB
Coordinates: save as pdb, mmCIF, xml



Wild Type RNA Polymerase II


Overview

The x-ray structure of complete RNA polymerase II from Saccharomyces cerevisiae has been determined, including a heterodimer of subunits Rpb4 and Rpb7 not present in previous "core" polymerase II structures. The heterodimer maintains the polymerase in the conformation of a transcribing complex, may bind RNA as it emerges from the enzyme, and is in a position to interact with general transcription factors and the Mediator of transcriptional regulation.

About this Structure

1NIK is a Protein complex structure of sequences from Saccharomyces cerevisiae. Full crystallographic information is available from OCA.

Reference

Complete, 12-subunit RNA polymerase II at 4.1-A resolution: implications for the initiation of transcription., Bushnell DA, Kornberg RD, Proc Natl Acad Sci U S A. 2003 Jun 10;100(12):6969-73. Epub 2003 May 13. PMID:12746498

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