1nox
From Proteopedia
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|PDB= 1nox |SIZE=350|CAPTION= <scene name='initialview01'>1nox</scene>, resolution 1.59Å | |PDB= 1nox |SIZE=350|CAPTION= <scene name='initialview01'>1nox</scene>, resolution 1.59Å | ||
|SITE= <scene name='pdbsite=COF:Cofactor'>COF</scene> | |SITE= <scene name='pdbsite=COF:Cofactor'>COF</scene> | ||
| - | |LIGAND= <scene name='pdbligand=FMN:FLAVIN MONONUCLEOTIDE'>FMN</scene> | + | |LIGAND= <scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene> |
| - | |ACTIVITY= [http://en.wikipedia.org/wiki/NADH_dehydrogenase NADH dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.6.99.3 1.6.99.3] | + | |ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/NADH_dehydrogenase NADH dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.6.99.3 1.6.99.3] </span> |
|GENE= | |GENE= | ||
| + | |DOMAIN= | ||
| + | |RELATEDENTRY= | ||
| + | |RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1nox FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nox OCA], [http://www.ebi.ac.uk/pdbsum/1nox PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1nox RCSB]</span> | ||
}} | }} | ||
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[[Category: Schmid, R D.]] | [[Category: Schmid, R D.]] | ||
[[Category: Sprinzl, M.]] | [[Category: Sprinzl, M.]] | ||
| - | [[Category: FMN]] | ||
[[Category: flavoenzyme]] | [[Category: flavoenzyme]] | ||
[[Category: flavoprotein fmn]] | [[Category: flavoprotein fmn]] | ||
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[[Category: thermophile]] | [[Category: thermophile]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 22:33:24 2008'' |
Revision as of 19:33, 30 March 2008
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| , resolution 1.59Å | |||||||
|---|---|---|---|---|---|---|---|
| Sites: | |||||||
| Ligands: | |||||||
| Activity: | NADH dehydrogenase, with EC number 1.6.99.3 | ||||||
| Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
NADH OXIDASE FROM THERMUS THERMOPHILUS
Overview
The crystal structures of the flavin adenine dinucleotide (FAD) and flavin mononucleotide (FMN) containing isoforms of NADH oxidase from Thermus thermophilus have been determined by isomorphous and molecular replacement and refined to 2.3 A and 1.6 A resolution with R-values of 18.5% and 18.6% respectively. The structure of the homodimeric enzyme consists of a central 4-stranded antiparallel beta-sheet covered by helices, a more flexible domain formed by two helices, and a C-terminal excursion connecting the subunits. The active sites are located in a deep cleft between the subunits. The binding site of the flavin cofactor lacks the common nucleotide binding fold and is different from the FMN binding site found in flavodoxins.
About this Structure
1NOX is a Single protein structure of sequence from Thermus thermophilus. Full crystallographic information is available from OCA.
Reference
Crystal structure of NADH oxidase from Thermus thermophilus., Hecht HJ, Erdmann H, Park HJ, Sprinzl M, Schmid RD, Nat Struct Biol. 1995 Dec;2(12):1109-14. PMID:8846223
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