3zss
From Proteopedia
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==APO FORM OF GLGE ISOFORM 1 FROM STREPTOMYCES COELICOLOR== | ==APO FORM OF GLGE ISOFORM 1 FROM STREPTOMYCES COELICOLOR== | ||
<StructureSection load='3zss' size='340' side='right' caption='[[3zss]], [[Resolution|resolution]] 1.80Å' scene=''> | <StructureSection load='3zss' size='340' side='right' caption='[[3zss]], [[Resolution|resolution]] 1.80Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3zss]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[3zss]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/"actinomyces_coelicolor"_(muller_1908)_lieske_1921 "actinomyces coelicolor" (muller 1908) lieske 1921]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZSS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ZSS FirstGlance]. <br> |
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3zst|3zst]], [[3zt7|3zt7]], [[3zt6|3zt6]], [[3zt5|3zt5]]</td></tr> | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3zst|3zst]], [[3zt7|3zt7]], [[3zt6|3zt6]], [[3zt5|3zt5]]</td></tr> | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3zss FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zss OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3zss RCSB], [http://www.ebi.ac.uk/pdbsum/3zss PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3zss FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zss OCA], [http://pdbe.org/3zss PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3zss RCSB], [http://www.ebi.ac.uk/pdbsum/3zss PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3zss ProSAT]</span></td></tr> |
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/GLGE1_STRCO GLGE1_STRCO]] Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1->4)-glucans. Maltooligosaccharides with a degree of polymerization (DP) superior or equal to 4 are efficient acceptors, with DP6 being optimal in the GlgE-catalyzed polymerization with M1P. Is specific for the alpha-anomer of M1P as substrate, since the beta-anomer of M1P gives no activity. Alpha-D-glucose 1-phosphate cannot serve as a donor substrate, but alpha-maltosyl fluoride is an efficient donor in vitro. Exhibits an alpha-retaining catalytic mechanism, with evidence that maltooligosaccharide acceptors are extended at their non-reducing ends. Is also able to catalyze the reverse reaction in vitro, releasing M1P from glycogen or maltoheptaose in the presence of inorganic phosphate. Also catalyzes disproportionation reactions through maltosyl transfer between maltooligosaccharides. Is probably involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB.<ref>PMID:21914799</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
| + | <div class="pdbe-citations 3zss" style="background-color:#fffaf0;"></div> | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: Streptomyces coelicolor]] | ||
[[Category: Bornemann, S]] | [[Category: Bornemann, S]] | ||
[[Category: Bruton, C J]] | [[Category: Bruton, C J]] | ||
Revision as of 13:24, 11 August 2016
APO FORM OF GLGE ISOFORM 1 FROM STREPTOMYCES COELICOLOR
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