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2xh0

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==ENGINEERING THE ENOLASE ACTIVE SITE POCKET: CRYSTAL STRUCTURE OF THE S39N Q167K D321R MUTANT OF YEAST ENOLASE 1==
==ENGINEERING THE ENOLASE ACTIVE SITE POCKET: CRYSTAL STRUCTURE OF THE S39N Q167K D321R MUTANT OF YEAST ENOLASE 1==
<StructureSection load='2xh0' size='340' side='right' caption='[[2xh0]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
<StructureSection load='2xh0' size='340' side='right' caption='[[2xh0]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2xh0]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XH0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2XH0 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2xh0]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XH0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2XH0 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PEP:PHOSPHOENOLPYRUVATE'>PEP</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PEP:PHOSPHOENOLPYRUVATE'>PEP</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2xh2|2xh2]], [[2xgz|2xgz]], [[1p48|1p48]], [[1els|1els]], [[1ebg|1ebg]], [[1l8p|1l8p]], [[3enl|3enl]], [[4enl|4enl]], [[1p43|1p43]], [[5enl|5enl]], [[1nel|1nel]], [[2one|2one]], [[2xh7|2xh7]], [[2xh4|2xh4]], [[6enl|6enl]], [[1one|1one]], [[7enl|7enl]], [[1ebh|1ebh]], [[2al2|2al2]], [[2al1|2al1]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2xh2|2xh2]], [[2xgz|2xgz]], [[1p48|1p48]], [[1els|1els]], [[1ebg|1ebg]], [[1l8p|1l8p]], [[3enl|3enl]], [[4enl|4enl]], [[1p43|1p43]], [[5enl|5enl]], [[1nel|1nel]], [[2one|2one]], [[2xh7|2xh7]], [[2xh4|2xh4]], [[6enl|6enl]], [[1one|1one]], [[7enl|7enl]], [[1ebh|1ebh]], [[2al2|2al2]], [[2al1|2al1]]</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Phosphopyruvate_hydratase Phosphopyruvate hydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.11 4.2.1.11] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Phosphopyruvate_hydratase Phosphopyruvate hydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.11 4.2.1.11] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2xh0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xh0 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2xh0 RCSB], [http://www.ebi.ac.uk/pdbsum/2xh0 PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2xh0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xh0 OCA], [http://pdbe.org/2xh0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2xh0 RCSB], [http://www.ebi.ac.uk/pdbsum/2xh0 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2xh0 ProSAT]</span></td></tr>
</table>
</table>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
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<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2xh0 ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 2xh0" style="background-color:#fffaf0;"></div>
==See Also==
==See Also==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Atcc 18824]]
[[Category: Phosphopyruvate hydratase]]
[[Category: Phosphopyruvate hydratase]]
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[[Category: Saccharomyces cerevisiae]]
 
[[Category: Hocker, B]]
[[Category: Hocker, B]]
[[Category: Schreier, B]]
[[Category: Schreier, B]]

Revision as of 15:31, 11 August 2016

ENGINEERING THE ENOLASE ACTIVE SITE POCKET: CRYSTAL STRUCTURE OF THE S39N Q167K D321R MUTANT OF YEAST ENOLASE 1

2xh0, resolution 1.70Å

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