9hvp
From Proteopedia
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==Design, activity and 2.8 Angstroms crystal structure of a C2 symmetric inhibitor complexed to HIV-1 protease== | ==Design, activity and 2.8 Angstroms crystal structure of a C2 symmetric inhibitor complexed to HIV-1 protease== | ||
<StructureSection load='9hvp' size='340' side='right' caption='[[9hvp]], [[Resolution|resolution]] 2.80Å' scene=''> | <StructureSection load='9hvp' size='340' side='right' caption='[[9hvp]], [[Resolution|resolution]] 2.80Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[9hvp]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[9hvp]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/9hiv1 9hiv1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9HVP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=9HVP FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=0E9:BENZYL+[(1R,4S,6S,9R)-4,6-DIBENZYL-5-HYDROXY-1,9-BIS(1-METHYLETHYL)-2,8,11-TRIOXO-13-PHENYL-12-OXA-3,7,10-TRIAZATRIDEC-1-YL]CARBAMATE'>0E9</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=0E9:BENZYL+[(1R,4S,6S,9R)-4,6-DIBENZYL-5-HYDROXY-1,9-BIS(1-METHYLETHYL)-2,8,11-TRIOXO-13-PHENYL-12-OXA-3,7,10-TRIAZATRIDEC-1-YL]CARBAMATE'>0E9</scene></td></tr> | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=9hvp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9hvp OCA], [http://www.rcsb.org/pdb/explore.do?structureId=9hvp RCSB], [http://www.ebi.ac.uk/pdbsum/9hvp PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=9hvp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9hvp OCA], [http://pdbe.org/9hvp PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=9hvp RCSB], [http://www.ebi.ac.uk/pdbsum/9hvp PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=9hvp ProSAT]</span></td></tr> |
</table> | </table> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
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<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
| - | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/ | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=9hvp ConSurf]. |
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
| + | <div class="pdbe-citations 9hvp" style="background-color:#fffaf0;"></div> | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: Human immunodeficiency virus 1]] | ||
[[Category: Erickson, J]] | [[Category: Erickson, J]] | ||
[[Category: Neidhart, D J]] | [[Category: Neidhart, D J]] | ||
[[Category: Acid proteinase]] | [[Category: Acid proteinase]] | ||
[[Category: Hydrolase-hydrolase inhibitor complex]] | [[Category: Hydrolase-hydrolase inhibitor complex]] | ||
Revision as of 16:27, 11 August 2016
Design, activity and 2.8 Angstroms crystal structure of a C2 symmetric inhibitor complexed to HIV-1 protease
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