3sa4

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==Crystal structure of wild-type HIV-1 protease in complex with AF72==
==Crystal structure of wild-type HIV-1 protease in complex with AF72==
<StructureSection load='3sa4' size='340' side='right' caption='[[3sa4]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
<StructureSection load='3sa4' size='340' side='right' caption='[[3sa4]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3sa4]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SA4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3SA4 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3sa4]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/9hiv1 9hiv1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SA4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3SA4 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=F72:N-{(2S,3R)-4-[(1,3-BENZOTHIAZOL-6-YLSULFONYL)(CYCLOHEXYLMETHYL)AMINO]-3-HYDROXY-1-PHENYLBUTAN-2-YL}-3-HYDROXYBENZAMIDE'>F72</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=F72:N-{(2S,3R)-4-[(1,3-BENZOTHIAZOL-6-YLSULFONYL)(CYCLOHEXYLMETHYL)AMINO]-3-HYDROXY-1-PHENYLBUTAN-2-YL}-3-HYDROXYBENZAMIDE'>F72</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3sa3|3sa3]], [[3sa5|3sa5]], [[3sa6|3sa6]], [[3sa7|3sa7]], [[3sa8|3sa8]], [[3sa9|3sa9]], [[3saa|3saa]], [[3sab|3sab]], [[3sac|3sac]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3sa3|3sa3]], [[3sa5|3sa5]], [[3sa6|3sa6]], [[3sa7|3sa7]], [[3sa8|3sa8]], [[3sa9|3sa9]], [[3saa|3saa]], [[3sab|3sab]], [[3sac|3sac]]</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">gag-pol, pol ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11676 Human immunodeficiency virus 1])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">gag-pol, pol ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11676 9HIV1])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3sa4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3sa4 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3sa4 RCSB], [http://www.ebi.ac.uk/pdbsum/3sa4 PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3sa4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3sa4 OCA], [http://pdbe.org/3sa4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3sa4 RCSB], [http://www.ebi.ac.uk/pdbsum/3sa4 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3sa4 ProSAT]</span></td></tr>
</table>
</table>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human immunodeficiency virus 1]]
 
[[Category: Nalam, M N.L]]
[[Category: Nalam, M N.L]]
[[Category: Schiffer, C A]]
[[Category: Schiffer, C A]]

Revision as of 16:55, 11 August 2016

Crystal structure of wild-type HIV-1 protease in complex with AF72

3sa4, resolution 1.80Å

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