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4a2u

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==CRP(CAP) from Myco. Tuberculosis, with cAMP==
==CRP(CAP) from Myco. Tuberculosis, with cAMP==
<StructureSection load='4a2u' size='340' side='right' caption='[[4a2u]], [[Resolution|resolution]] 2.63&Aring;' scene=''>
<StructureSection load='4a2u' size='340' side='right' caption='[[4a2u]], [[Resolution|resolution]] 2.63&Aring;' scene=''>
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<table><tr><td colspan='2'>[[4a2u]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Myctu Myctu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4A2U OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4A2U FirstGlance]. <br>
<table><tr><td colspan='2'>[[4a2u]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Myctu Myctu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4A2U OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4A2U FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CMP:ADENOSINE-3,5-CYCLIC-MONOPHOSPHATE'>CMP</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CMP:ADENOSINE-3,5-CYCLIC-MONOPHOSPHATE'>CMP</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4a2u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4a2u OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4a2u RCSB], [http://www.ebi.ac.uk/pdbsum/4a2u PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4a2u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4a2u OCA], [http://pdbe.org/4a2u PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4a2u RCSB], [http://www.ebi.ac.uk/pdbsum/4a2u PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4a2u ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/O69644_MYCTU O69644_MYCTU]] Global transcriptional regulator that complexes with cAMP and binds to specific DNA promoter sites, causing DNA-bending, to regulate transcription. cAMP improves binding to specific DNA sequences, probably by altering protein conformation. Activates expression of whiB1.<ref>PMID:16946269</ref>
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[[http://www.uniprot.org/uniprot/CRP_MYCTO CRP_MYCTO]] Global transcriptional regulator that complexes with cAMP and binds to specific DNA promoter sites, causing DNA-bending, to regulate transcription. cAMP improves binding to specific DNA sequences, probably by altering protein conformation. Activates expression of whiB1.<ref>PMID:16946269</ref>
== References ==
== References ==
<references/>
<references/>

Revision as of 18:39, 11 August 2016

CRP(CAP) from Myco. Tuberculosis, with cAMP

4a2u, resolution 2.63Å

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