Phosphotriesterase

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== Structural highlights ==
== Structural highlights ==
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The reaction product of PTE is located in the binuclear metal center<ref>PMID:18702530</ref>.
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The <scene name='48/489268/Cv/3'>reaction product of PTE is located in the binuclear metal center</scene><ref>PMID:18702530</ref>.Water molecules shown as red spheres.
</StructureSection>
</StructureSection>
==3D structures of phosphotriesterase==
==3D structures of phosphotriesterase==

Revision as of 12:07, 15 August 2016

Phosphotriesterase dimer complex with reaction product ethyl phosphate and Co+2 ion (pink), 3cak

Drag the structure with the mouse to rotate

3D structures of phosphotriesterase

Updated on 15-August-2016

References

  1. Roodveldt C, Tawfik DS. Directed evolution of phosphotriesterase from Pseudomonas diminuta for heterologous expression in Escherichia coli results in stabilization of the metal-free state. Protein Eng Des Sel. 2005 Jan;18(1):51-8. PMID:15790580 doi:http://dx.doi.org/10.1093/protein/gzi005
  2. Bigley AN, Mabanglo MF, Harvey SP, Raushel FM. Variants of Phosphotriesterase for the Enhanced Detoxification of the Chemical Warfare Agent VR. Biochemistry. 2015 Aug 25. PMID:26274608 doi:http://dx.doi.org/10.1021/acs.biochem.5b00629
  3. Kim J, Tsai PC, Chen SL, Himo F, Almo SC, Raushel FM. Structure of diethyl phosphate bound to the binuclear metal center of phosphotriesterase. Biochemistry. 2008 Sep 9;47(36):9497-504. Epub 2008 Aug 15. PMID:18702530 doi:10.1021/bi800971v

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Joel L. Sussman, Alexander Berchansky

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