This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


Ribozyme

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
<Structure load='379d' size='400' scene='Ribozyme/Cv/3' frame='true' align='right' caption='Hammerhead ribozyme, [[379d]]'/>
<Structure load='379d' size='400' scene='Ribozyme/Cv/3' frame='true' align='right' caption='Hammerhead ribozyme, [[379d]]'/>
-
[[Ribozyme]] (RZ) is an RNA molecule which catalyzes a chemical reaction. The '''Glucosamine-6-phosphate activated RZ''' (glmS RZ) is a RZ and a riboswitch which regulates genes in response to metabolites. '''Leadzyme''' is a small, artificially-made RZ which can cleave RNA in the presence of lead. For more details on leadzyme see [[Student Projects for UMass Chemistry 423 Spring 2012-10]]. '''Hairpin RZ''' and '''hammerhead RZ''' are named based on their shape. The '''group I intron''' catalyzes its own selfish splicing.
+
[[Ribozyme]] (RZ) is an RNA molecule which catalyzes a chemical reaction<ref>PMID:9224568</ref>.<br />
 +
*'''Glucosamine-6-phosphate activated RZ''' (glmS RZ) is a RZ and a riboswitch which regulates genes in response to metabolites.<br />
 +
*'''Leadzyme''' is a small, artificially-made RZ which can cleave RNA in the presence of lead. For more details on leadzyme see [[Student Projects for UMass Chemistry 423 Spring 2012-10]].<br />
 +
*'''Hairpin RZ''' and '''hammerhead RZ''' are named based on their shape<ref>PMID:9849614</ref>.<br />
 +
*'''Group I intron''' catalyzes its own selfish splicing<ref>PMID:2197983</ref>.
Articles in Proteopedia concerning ribozymes include:
Articles in Proteopedia concerning ribozymes include:
Line 100: Line 104:
**[[1u6b]], [[1zzn]], [[3bo2]], [[3bo3]], [[3bo4]], [[3iin]] - ''Azoarcus'' group I intron <br/>
**[[1u6b]], [[1zzn]], [[3bo2]], [[3bo3]], [[3bo4]], [[3iin]] - ''Azoarcus'' group I intron <br/>
}}
}}
 +
== References ==
 +
<references/>
[[Category: Topic Page]]
[[Category: Topic Page]]

Revision as of 09:05, 17 August 2016

Hammerhead ribozyme, 379d

Drag the structure with the mouse to rotate

Ribozyme (RZ) is an RNA molecule which catalyzes a chemical reaction[1].

  • Glucosamine-6-phosphate activated RZ (glmS RZ) is a RZ and a riboswitch which regulates genes in response to metabolites.
  • Leadzyme is a small, artificially-made RZ which can cleave RNA in the presence of lead. For more details on leadzyme see Student Projects for UMass Chemistry 423 Spring 2012-10.
  • Hairpin RZ and hammerhead RZ are named based on their shape[2].
  • Group I intron catalyzes its own selfish splicing[3].

Articles in Proteopedia concerning ribozymes include:


To view automatically seeded indices concerning ribozymes, see:

3D Structures of Ribozymes

Updated on 17-August-2016

References

  1. ↑ Tang J, Breaker RR. Rational design of allosteric ribozymes. Chem Biol. 1997 Jun;4(6):453-9. PMID:9224568
  2. ↑ Amarzguioui M, Prydz H. Hammerhead ribozyme design and application. Cell Mol Life Sci. 1998 Nov;54(11):1175-202. PMID:9849614 doi:http://dx.doi.org/10.1007/s000180050247
  3. ↑ Cech TR. Self-splicing of group I introns. Annu Rev Biochem. 1990;59:543-68. PMID:2197983 doi:http://dx.doi.org/10.1146/annurev.bi.59.070190.002551

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Wayne Decatur, Joel L. Sussman, Alexander Berchansky

Retrieved from "http://52.214.119.220/wiki/index.php/Ribozyme"
Personal tools