Ribozyme

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
<Structure load='379d' size='400' scene='Ribozyme/Cv/3' frame='true' align='right' caption='Hammerhead ribozyme, [[379d]]'/>
<Structure load='379d' size='400' scene='Ribozyme/Cv/3' frame='true' align='right' caption='Hammerhead ribozyme, [[379d]]'/>
-
[[Ribozyme]] (RZ) is an RNA molecule which catalyzes a chemical reaction. The '''Glucosamine-6-phosphate activated RZ''' (glmS RZ) is a RZ and a riboswitch which regulates genes in response to metabolites. '''Leadzyme''' is a small, artificially-made RZ which can cleave RNA in the presence of lead. For more details on leadzyme see [[Student Projects for UMass Chemistry 423 Spring 2012-10]]. '''Hairpin RZ''' and '''hammerhead RZ''' are named based on their shape. The '''group I intron''' catalyzes its own selfish splicing.
+
[[Ribozyme]] (RZ) is an RNA molecule which catalyzes a chemical reaction<ref>PMID:9224568</ref>.<br />
 +
*'''Glucosamine-6-phosphate activated RZ''' (glmS RZ) is a RZ and a riboswitch which regulates genes in response to metabolites.<br />
 +
*'''Leadzyme''' is a small, artificially-made RZ which can cleave RNA in the presence of lead. For more details on leadzyme see [[Student Projects for UMass Chemistry 423 Spring 2012-10]].<br />
 +
*'''Hairpin RZ''' and '''hammerhead RZ''' are named based on their shape<ref>PMID:9849614</ref>.<br />
 +
*'''Group I intron''' catalyzes its own selfish splicing<ref>PMID:2197983</ref>.
Articles in Proteopedia concerning ribozymes include:
Articles in Proteopedia concerning ribozymes include:
Line 100: Line 104:
**[[1u6b]], [[1zzn]], [[3bo2]], [[3bo3]], [[3bo4]], [[3iin]] - ''Azoarcus'' group I intron <br/>
**[[1u6b]], [[1zzn]], [[3bo2]], [[3bo3]], [[3bo4]], [[3iin]] - ''Azoarcus'' group I intron <br/>
}}
}}
 +
== References ==
 +
<references/>
[[Category: Topic Page]]
[[Category: Topic Page]]

Revision as of 09:05, 17 August 2016

Hammerhead ribozyme, 379d

Drag the structure with the mouse to rotate

Ribozyme (RZ) is an RNA molecule which catalyzes a chemical reaction[1].

  • Glucosamine-6-phosphate activated RZ (glmS RZ) is a RZ and a riboswitch which regulates genes in response to metabolites.
  • Leadzyme is a small, artificially-made RZ which can cleave RNA in the presence of lead. For more details on leadzyme see Student Projects for UMass Chemistry 423 Spring 2012-10.
  • Hairpin RZ and hammerhead RZ are named based on their shape[2].
  • Group I intron catalyzes its own selfish splicing[3].

Articles in Proteopedia concerning ribozymes include:


To view automatically seeded indices concerning ribozymes, see:

3D Structures of Ribozymes

Updated on 17-August-2016

References

  1. ↑ Tang J, Breaker RR. Rational design of allosteric ribozymes. Chem Biol. 1997 Jun;4(6):453-9. PMID:9224568
  2. ↑ Amarzguioui M, Prydz H. Hammerhead ribozyme design and application. Cell Mol Life Sci. 1998 Nov;54(11):1175-202. PMID:9849614 doi:http://dx.doi.org/10.1007/s000180050247
  3. ↑ Cech TR. Self-splicing of group I introns. Annu Rev Biochem. 1990;59:543-68. PMID:2197983 doi:http://dx.doi.org/10.1146/annurev.bi.59.070190.002551

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Wayne Decatur, Joel L. Sussman, Alexander Berchansky

Retrieved from "http://52.214.119.220/wiki/index.php/Ribozyme"
Personal tools