Methionine adenosyltransferase

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Line 17: Line 17:
**[[1fug]] – EcMAT – ''Escherichia coli''<br />
**[[1fug]] – EcMAT – ''Escherichia coli''<br />
**[[3iml]] – MAT – ''Burkholderia pseudomallei''<br />
**[[3iml]] – MAT – ''Burkholderia pseudomallei''<br />
-
**[[2ydy]] – hMAT II subunit β – human
+
**[[2ydy]] – hMAT II subunit β – human<br />
 +
**[[4le5]] – MAT- ''Campylobacter jejuni''<br />
 +
**[[4hpv]] - SsMAT – ''Sulfolobus solfataricus''<br />
 +
**[[3tde]] – MAT- ''Mycobacterium tuberculosis''<br />
 +
**[[3s82]] – MAT- ''Mycobacterium avium''<br />
 +
**[[3rv2]] – MAT- ''Mycobacterium marinum''<br />
 +
 
*S-adenosylmethionine synthetase complexes
*S-adenosylmethionine synthetase complexes
Line 35: Line 41:
**[[2obv]] – hMAT I + AdoMet + Na <br />
**[[2obv]] – hMAT I + AdoMet + Na <br />
**[[2p02]] - hMAT II + AdoMet<br />
**[[2p02]] - hMAT II + AdoMet<br />
-
**[[2ydx]] – MAT + resveratrol + NADP + Ca + ADP derivative
+
**[[2ydx]] – MAT + resveratrol + NADP + Ca + ADP derivative<br />
 +
**[[4l2z]], [[4k0b]] - SsMAT + Pi + PPi + Mg + SAM derivative <br />
}}
}}
== References ==
== References ==
<references/>
<references/>
[[Category:Topic Page]]
[[Category:Topic Page]]

Revision as of 10:20, 22 August 2016

The dimeric rat S-adenosylmethionine synthetase complex with methionine, phosphate, ATP (stick model), Mg+2 (green), phosphate and K+ (purple) ions (PDB entry 1o9t)

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3D structures of S-adenosylmethionine synthetase

22-August-2016


References

  1. Takusagawa F, Kamitori S, Markham GD. Structure and function of S-adenosylmethionine synthetase: crystal structures of S-adenosylmethionine synthetase with ADP, BrADP, and PPi at 28 angstroms resolution. Biochemistry. 1996 Feb 27;35(8):2586-96. PMID:8611562 doi:http://dx.doi.org/10.1021/bi952604z
  2. Mato JM, Alvarez L, Ortiz P, Mingorance J, Duran C, Pajares MA. S-adenosyl-L-methionine synthetase and methionine metabolism deficiencies in cirrhosis. Adv Exp Med Biol. 1994;368:113-7. PMID:7741002
  3. Gonzalez B, Pajares MA, Hermoso JA, Guillerm D, Guillerm G, Sanz-Aparicio J. Crystal structures of methionine adenosyltransferase complexed with substrates and products reveal the methionine-ATP recognition and give insights into the catalytic mechanism. J Mol Biol. 2003 Aug 8;331(2):407-16. PMID:12888348
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